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Factors associated with delirium among survivors of acute respiratory distress syndrome: a nationwide cohort study
DC Field | Value | Language |
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dc.contributor.author | Oh, Tak Kyu | - |
dc.contributor.author | Park, Hye Youn | - |
dc.contributor.author | Song, In-Ae | - |
dc.date.accessioned | 2022-02-21T00:41:08Z | - |
dc.date.available | 2022-02-21T09:42:48Z | - |
dc.date.issued | 2021-11-01 | - |
dc.identifier.citation | BMC Pulmonary Medicine. 2021 Nov 01;21(1):341 | ko_KR |
dc.identifier.issn | 1465-993X | - |
dc.identifier.uri | https://hdl.handle.net/10371/176964 | - |
dc.description.abstract | Background
The prevalence of delirium, its associated factors, and its impact on long-term mortality among survivors of acute respiratory distress syndrome (ARDS) is unclear. Methods Since this was a population-based study, data were extracted from the National Health Insurance database in South Korea. All adults who were admitted to intensive care units with a diagnosis of ARDS between January 1, 2010, and December 31, 2019, and who survived for ≥ 60days were included. The International Statistical Classification of Diseases and Related Health Problems, tenth revision code of delirium (F05) was used to extract delirium cases during hospitalization. Results A total of 6809 ARDS survivors were included in the analysis, and 319 patients (4.7%) were diagnosed with delirium during hospitalization. In the multivariable logistic regression analysis after covariate adjustment, male sex (odds ratio [OR] 1.60, 95% confidence interval [CI] 1.23, 2.08; P < 0.001), longer duration of hospitalization (OR 1.02, 95% CI 1.01, 1.03; P < 0.001), neuromuscular blockade use (OR 1.50, 95% CI 1.12, 2.01; P = 0.006), benzodiazepine (OR 1.55, 95% CI 1.13, 2.13; P = 0.007) and propofol (OR 1.48, 95% CI 1.01, 2.17; P = 0.046) continuous infusion, and concurrent depression (OR 1.31, 95% CI 1.01, 1.71; P = 0.044) were associated with a higher prevalence of delirium among ARDS survivors. In the multivariable Cox regression analysis after adjustment for covariates, the occurrence of delirium was not significantly associated with 1-year all-cause mortality, when compared to the other survivors who did not develop delirium (hazard ratio: 0.85, 95% CI 1.01, 1.71; P = 0.044). Conclusions In South Korea, 4.7% of ARDS survivors were diagnosed with delirium during hospitalization in South Korea. Some factors were potential risk factors for the development of delirium, but the occurrence of delirium might not affect 1-year all-cause mortality among ARDS survivors. | ko_KR |
dc.description.sponsorship | This research did not receive any specifc grant from funding agencies in the public, commercial, or not-for-proft sectors. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BMC | ko_KR |
dc.subject | Critical Care | - |
dc.subject | Delirium | - |
dc.subject | Mortality | - |
dc.subject | Respiratory distress syndrome | - |
dc.title | Factors associated with delirium among survivors of acute respiratory distress syndrome: a nationwide cohort study | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 오탁규 | - |
dc.contributor.AlternativeAuthor | 박혜윤 | - |
dc.contributor.AlternativeAuthor | 송인애 | - |
dc.identifier.doi | https://doi.org/10.1186/s12890-021-01714-0 | - |
dc.citation.journaltitle | BMC Pulmonary Medicine | ko_KR |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s) | - |
dc.date.updated | 2021-11-07T04:14:56Z | - |
dc.citation.number | 1 | ko_KR |
dc.citation.startpage | 341 | ko_KR |
dc.citation.volume | 21 | ko_KR |
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