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Radioactive iodine therapy did not significantly increase the incidence and recurrence of subsequent breast cancer
DC Field | Value | Language |
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dc.contributor.author | Ahn, Hwa Young | - |
dc.contributor.author | Min, Hye Sook | - |
dc.contributor.author | Yeo, Yohwan | - |
dc.contributor.author | Ma, Seung Hyun | - |
dc.contributor.author | Hwang, Yunji | - |
dc.contributor.author | An, Jee Hyun | - |
dc.contributor.author | Choi, Hoon Sung | - |
dc.contributor.author | Keam, Bhumsuk | - |
dc.contributor.author | Im, Seock-Ah | - |
dc.contributor.author | Park, Do Joon | - |
dc.contributor.author | Park, In Ae | - |
dc.contributor.author | Noh, Dong-Young | - |
dc.contributor.author | Youn, Yeo-Kyu | - |
dc.contributor.author | Chung, June-Key | - |
dc.contributor.author | Cho, Bo Youn | - |
dc.contributor.author | Park, Sue Kyung | - |
dc.contributor.author | Park, Young Joo | - |
dc.date.accessioned | 2022-03-22T09:22:07Z | - |
dc.date.available | 2022-03-22T09:22:07Z | - |
dc.date.created | 2018-11-01 | - |
dc.date.created | 2018-11-01 | - |
dc.date.issued | 2015-09 | - |
dc.identifier.citation | Journal of Clinical Endocrinology and Metabolism, Vol.100 No.9, pp.3486-3493 | - |
dc.identifier.issn | 0021-972X | - |
dc.identifier.other | 65020 | - |
dc.identifier.uri | https://hdl.handle.net/10371/177266 | - |
dc.description.abstract | Context: Previous studies on the extent to which radioactive iodine (RAI) therapy for thyroid cancer increases the risk of subsequently developing breast cancer have given conflicting results. Objective: This study aimed to evaluate the effect of RAI treatment on breast cancer development and recurrence among female patients with primary thyroid cancer. Design: This was a retrospective cohort study. The risk of subsequent breast cancer associated with RAI and its dose in hazard ratios (HRs) with 95% confidential intervals (CIs) were calculated using time-dependent Cox proportional hazard models. Patients: A total of 6150 patients with thyroid cancer enrolled between 1973 and 2009 were followed until December 2012. Of these, 3631 (59.0%) received RAI therapy. During the follow-up period, 99 primary breast cancers were diagnosed. Main Outcome Measure: Risk of breast cancer development according to RAI therapy and RAI dose during treatment for primary thyroid cancer. Results: RAI therapy did not significantly increase the incidence of subsequent breast cancer among female patients (hazard ratio [HR], 0.49; 95% confidence interval [CI], 0.22-1.06) when a 2-year latency period was accounted for. High-dose RAI (>= 120 mCi) was associated with a reduced incidence of subsequent breast cancer (HR, 0.17; 95% CI, 0.05-0.62) in the cohort with a 2-year latency period. Conclusions: The long-term follow-up results of this study suggest that RAI treatment for patients with thyroid cancer may not increase the risk or recurrence of breast cancer. | - |
dc.language | 영어 | - |
dc.publisher | The Endocrine Society | - |
dc.title | Radioactive iodine therapy did not significantly increase the incidence and recurrence of subsequent breast cancer | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 임석아 | - |
dc.identifier.doi | 10.1210/JC.2014-2896 | - |
dc.citation.journaltitle | Journal of Clinical Endocrinology and Metabolism | - |
dc.identifier.wosid | 000364867800057 | - |
dc.identifier.scopusid | 2-s2.0-84941730255 | - |
dc.citation.endpage | 3493 | - |
dc.citation.number | 9 | - |
dc.citation.startpage | 3486 | - |
dc.citation.volume | 100 | - |
dc.identifier.sci | 000364867800057 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Im, Seock-Ah | - |
dc.contributor.affiliatedAuthor | Park, Do Joon | - |
dc.contributor.affiliatedAuthor | Park, In Ae | - |
dc.contributor.affiliatedAuthor | Noh, Dong-Young | - |
dc.contributor.affiliatedAuthor | Youn, Yeo-Kyu | - |
dc.contributor.affiliatedAuthor | Chung, June-Key | - |
dc.contributor.affiliatedAuthor | Cho, Bo Youn | - |
dc.contributor.affiliatedAuthor | Park, Sue Kyung | - |
dc.contributor.affiliatedAuthor | Park, Young Joo | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | 2ND PRIMARY MALIGNANCY | - |
dc.subject.keywordPlus | ATOMIC-BOMB SURVIVORS | - |
dc.subject.keywordPlus | THYROID-CANCER | - |
dc.subject.keywordPlus | PRIMARY TUMORS | - |
dc.subject.keywordPlus | I-131 THERAPY | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | RADIATION | - |
dc.subject.keywordPlus | WOMEN | - |
dc.subject.keywordPlus | HYPERTHYROIDISM | - |
dc.subject.keywordPlus | RADIOIODINE | - |
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