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Neuroprotective and cognition-enhancing coumarins of angelica gigas : 참당귀의 뇌신경세포 보호활성 및 기억력 개선활성 coumarin계 성분
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- Authors
- Advisor
- 김영중
- Issue Date
- 2003
- Publisher
- 서울대학교 대학원
- Keywords
- Angelica gigas ; 알츠하이머씨병 ; Primary cultures of rat cortical neurons ; 아세틸콜린에스터라제 저해활성 ; Glutamate –induced neurotoxicity ; 글루타메이트 ; Acetylcholinesterase inhibitory activity ; 일차배양 대뇌피질세포 ; 4"-hydroxytigloyldecursinol (1) ; 4"-hydroxydecursin (2) ; 3``-butylxanthoarnol ; (2"S, 3"S)-epoxyangeloyldecursinol (3) ; (2"R, 3"R)-epoxyangeloyldecursinol (4) ; 3``-butylxanthoarnol (5) ; Decursin ; decursinol ; Scopolamine ; 스코폴라민 ; Cognition-enhancing activity ; 기억력 개선 ; Passive avoidance test ; 수동회피반응 시험 ; Morris water maze test ; 수미로 시험
- Description
- Thesis (doctoral)--서울대학교 대학원 :약학과 생약학전공,2003.
- Language
- English
- URI
- http://dcollection.snu.ac.kr:80/jsp/common/DcLoOrgPer.jsp?sItemId=000000059378
https://hdl.handle.net/10371/18456
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