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Dual action of a tyrosinase–mesoporous silica nanoparticle complex for synergistic tissue adhesion : Dual action of a tyrosinase-mesoporous silica nanoparticle complex for synergistic tissue adhesion

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Authors

Kim, Su-Hwan; Shin, Kwangsoo; Kim, Byung-Gee; Hwang, Nathaniel S. S.; Hyeon, Taeghwan

Issue Date
2022-11
Publisher
Royal Society of Chemistry
Citation
Chemical Communications, Vol.59 No.1, pp.94-97
Abstract
Bridging biological tissues for immediate adhesion and long-term sustainability was accomplished using a combination of mesoporous silica nanoparticles (MSNs) and tyrosinase. Tyrosinase-loaded MSNs provided rapid physical adsorption, while tyrosinase within MSNs induced enzymatic chemical bond gluing of tissues. This synergistic strategy has robust potential in tissue adhesives for clinical settings.
ISSN
1359-7345
URI
https://hdl.handle.net/10371/189418
DOI
https://doi.org/10.1039/d2cc05678j
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