Accelerating Drug Discovery and Development: Translational Medicine in Combating the COVID-19 Pandemic

Abstract

The world was struck by SARS-CoV-2 (COVID-19) unexpectedly at the end of 2019. The initial small-scale infection quickly turned into a pandemic that affected every corner of the world. In order to provide adequate treatment to the infected population and curb the spread of the virus, the world united as one in this unprecedented war of humans versus pathogens. Moreover, the world faces a greater challenge in the post-pandemic recovery and prevention of the next pandemic. In this chapter, we leveraged the principles of translational medicine to illustrate the fundamental discoveries and revolutionary technologies in virus detection clinical treatment, and vaccine development. The knowledge and experience garnered will undoubtedly impact and benefit the future of drug discovery and development. © 2022 John Wiley & Sons, Inc. All rights reserved.