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Mycangimycin, a Polyene Peroxide from a Mutualist Streptomyces sp.

Cited 128 time in Web of Science Cited 139 time in Scopus
Authors

Oh, Dong-Chan; Scott, Jarrod J.; Currie, Cameron R.; Clardy, Jon

Issue Date
2009-02
Publisher
American Chemical Society
Citation
Organic Letters, Vol.11 No.3, pp.633-636
Abstract
A mutualist actinomycete of the southern pine beetle, Dendroctonus frontalis, produces a polyene peroxide with pronounced antifungal activity. Its structure, absolute configuration, and biological activity were determined by spectral analysis, chemical modification followed by the modified Mosher method, and growth inhibitory assays, respectively.
ISSN
1523-7060
URI
https://hdl.handle.net/10371/208281
DOI
https://doi.org/10.1021/ol802709x
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  • College of Pharmacy
  • Department of Manufacturing Pharmacy
Research Area Chemical biology of natural products, Drug discovery from microbial natural products, Study of insect-microbial symbiosis, 미생물 유래 생리활성 천연물 발굴, 천연물 구조 분석

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