S-Space College of Medicine/School of Medicine (의과대학/대학원) Neuroscience (뇌신경과학전공) Journal Papers (저널논문_뇌신경과학전공)
Effect of the number of response alternatives on brain activity in response selection
- Woo, S. H.; Lee, K. M.
- Issue Date
- Hum Brain Mapp. 2007 Oct;28(10):950-8.
- Adult; Brain Mapping; Cerebral Cortex/anatomy & histology/*physiology; Cognition/*physiology; Cues; Decision Making/*physiology; Evoked Potentials/*physiology; Female; Functional Laterality/physiology; Gyrus Cinguli/anatomy & histology/physiology; Humans; Information Theory; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Parietal Lobe/anatomy & histology/physiology; Photic Stimulation; Prefrontal Cortex/anatomy & histology/physiology; Psychomotor Performance/*physiology; Reaction Time/*physiology; Temporal Lobe/anatomy & histology/physiology; Time Factors; Visual Cortex/anatomy & histology/physiology
- It is well-known in motor control literature that a response time (RT) increases as a logarithmic function of the number of response alternatives (NA) (Hick's law). In this study, we identified neural correlates for this relationship using event-related functional MRI and a choice finger-movement task. Behaviorally, average RTs of all subjects increased as a logarithmic function of the NA in accordance with the law. From a voxel-wise search for brain areas where the activity was correlated with NA and thence the RT, a positive correlation was found at the posterior cingulate and left superior frontal gyri, whereas a negative correlation was observed at areas in bilateral inferior parietal lobules. This differential modulation by the task context, namely, the NA available for a choice response with identical stimulus and response, indicates that these regions are involved in various aspects of response selection, intentional retrieval of motor program, or spatial expectancy.
- 1065-9471 (Print)
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