S-Space College of Medicine/School of Medicine (의과대학/대학원) Radiation Oncology (방사선종양학전공) Journal Papers (저널논문_방사선종양학전공)
Optic pathway glioma: outcome and prognostic factors in a surgical series
- Ahn, Yong; Cho, Byung-Kyu; Kim, Seung-Ki; Chung, You-Nam; Lee, Chang Sub; Kim, Il Han; Yang, Sei Won; Kim, Hee-Soo; Kim, Hyun Jib; Jung, Hee-Won; Wang, Kyu-Chang
- Issue Date
- Springer Verlag
- Childs Nerv Syst. 2006 Sep;22(9):1136-42. Epub 2006 Apr 21.
- Adolescent; Age Factors; Child; Child, Preschool; Disease Progression; Disease-Free Survival; Dominance, Cerebral/physiology; Female; Humans; Hypothalamic Neoplasms/pathology/surgery; Infant; Male; Neurologic Examination; Optic Chiasm/pathology/surgery; Optic Nerve Glioma/diagnosis/mortality/pathology/*surgery; Postoperative Complications/etiology/surgery; Prognosis; Reoperation; Retrospective Studies; Sex Factors; Survival Rate
- OBJECTS: The goals of this study were to evaluate the surgical outcomes of optic pathway glioma (OPG) and to analyze the prognostic factors related to the progression-free survival. MATERIALS AND METHODS: A retrospective review was conducted on 33 patients who underwent surgery for OPG; these included 15 male and 18 female patients with a mean age of 8.3 years. The mean duration of follow-up was 52 months. RESULTS AND CONCLUSIONS: The preservation rate of ipsilateral vision was 25%, while that of contralateral vision was 83% (P<0.001). There was no remarkable endocrine improvement after surgery. The overall and progression-free survival rates at 5 years were 93.6 and 52.4%, respectively. In our study, the predictors for tumor progression were children younger than 5 years of age (p=0.023) and of female gender (p=0.022). Because of the variable course of OPG, treatment policy should be optimized individually according to patient's status.
- 0256-7040 (Print)
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