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College of Medicine/School of Medicine (의과대학/대학원)
Radiation Oncology (방사선종양학전공)
Journal Papers (저널논문_방사선종양학전공)
Optic pathway glioma: outcome and prognostic factors in a surgical series
- Issue Date
- 2006-04-22
- Publisher
- Springer Verlag
- Citation
- Childs Nerv Syst. 2006 Sep;22(9):1136-42. Epub 2006 Apr 21.
- Keywords
- Adolescent ; Age Factors ; Child ; Child, Preschool ; Disease Progression ; Disease-Free Survival ; Dominance, Cerebral/physiology ; Female ; Humans ; Hypothalamic Neoplasms/pathology/surgery ; Infant ; Male ; Neurologic Examination ; Optic Chiasm/pathology/surgery ; Optic Nerve Glioma/diagnosis/mortality/pathology/*surgery ; Postoperative Complications/etiology/surgery ; Prognosis ; Reoperation ; Retrospective Studies ; Sex Factors ; Survival Rate
- Abstract
- OBJECTS: The goals of this study were to evaluate the surgical outcomes of optic pathway glioma (OPG) and to analyze the prognostic factors related to the progression-free survival. MATERIALS AND METHODS: A retrospective review was conducted on 33 patients who underwent surgery for OPG; these included 15 male and 18 female patients with a mean age of 8.3 years. The mean duration of follow-up was 52 months. RESULTS AND CONCLUSIONS: The preservation rate of ipsilateral vision was 25%, while that of contralateral vision was 83% (P<0.001). There was no remarkable endocrine improvement after surgery. The overall and progression-free survival rates at 5 years were 93.6 and 52.4%, respectively. In our study, the predictors for tumor progression were children younger than 5 years of age (p=0.023) and of female gender (p=0.022). Because of the variable course of OPG, treatment policy should be optimized individually according to patient's status.
- ISSN
- 0256-7040 (Print)
- Language
- English
- URI
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16628460
https://hdl.handle.net/10371/22911
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