Browse

The prevalence of and risk factors for erosive oesophagitis and non-erosive reflux disease: a nationwide multicentre prospective study in Korea

DC Field Value Language
dc.contributor.authorKim, N-
dc.contributor.authorLee, S W-
dc.contributor.authorCho, S I-
dc.contributor.authorPark, C G-
dc.contributor.authorYang, C H-
dc.contributor.authorKim, H S-
dc.contributor.authorRew, J S-
dc.contributor.authorMoon, J S-
dc.contributor.authorKim, S-
dc.contributor.authorPark, S H-
dc.contributor.authorJung, H C-
dc.contributor.authorChung, I S-
dc.date.accessioned2010-01-07T04:52:57Z-
dc.date.available2010-01-07T04:52:57Z-
dc.date.issued2007-11-02-
dc.identifier.citationAliment Pharmacol Ther. 2008 Jan 15;27(2):173-85. Epub 2007 Oct 25.en
dc.identifier.issn1365-2036 (Electronic)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17973646-
dc.identifier.urihttps://hdl.handle.net/10371/28167-
dc.description.abstractBACKGROUND: Prospective nationwide multicentre studies that have evaluated endoscopic findings and reflux symptoms using a well-designed questionnaire are very rare. AIM: To compare the prevalence rates of and risk factors for erosive oesophagitis and non-erosive reflux disease (NERD) in the Korean population. METHODS: A gastroscopic examination was performed on 25 536 subjects who visited 40 Healthcare Centers for a health check-up. A gastro-oesophageal reflux questionnaire and multivariate analysis were used to determine the risk factors for erosive oesophagitis and NERD. RESULTS: 2019 (8%) and 996 subjects (4%) had erosive oesophagitis and non-erosive reflux disease, respectively; only 58% of subjects with erosive oesophagitis had reflux symptoms. Multivariate analysis showed that the risk factors for erosive oesophagitis and NERD differed, i.e. those of erosive oesophagitis were male, a Helicobacter pylori eradication history, alcohol, body mass index > or =25 and hiatal hernia. In contrast, the risk factors for NERD were female, age <40 and > or =60 vs. 40-59 years, body mass index <23 and a monthly income <$1000, glucose > or =126 mg/dL, smoking, a stooping posture at work and antibiotic usage. CONCLUSIONS: The prevalence rates of erosive oesophagitis and NERD were 8% and 4%, respectively, in Korean health check-up subjects. The risk factors for erosive oesophagitis and NERD were found to differ, which indicates that their underlying pathogeneses are distinct.en
dc.language.isoenen
dc.publisherWiley-Blackwellen
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAlcoholic Beverages/adverse effectsen
dc.subjectBlood Glucose/metabolismen
dc.subjectBody Mass Indexen
dc.subjectEpidemiologic Factorsen
dc.subjectEsophagitis/*epidemiology/etiology/physiopathologyen
dc.subjectFemaleen
dc.subjectGastroesophageal Reflux/*epidemiologyen
dc.subjectGastroscopyen
dc.subjectHumansen
dc.subjectKorea/epidemiologyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPostureen
dc.subjectPrevalenceen
dc.subjectProspective Studiesen
dc.subjectSmoking/adverse effectsen
dc.titleThe prevalence of and risk factors for erosive oesophagitis and non-erosive reflux disease: a nationwide multicentre prospective study in Koreaen
dc.typeArticleen
dc.identifier.doi10.1111/j.1365-2036.2007.03561.x-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
Files in This Item:
There are no files associated with this item.
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse