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Asymmetrically altered integrity of cingulum bundle in posttraumatic stress disorder

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dc.contributor.authorKim, Seog Ju-
dc.contributor.authorJeong, Do-Un-
dc.contributor.authorSim, Minyoung E-
dc.contributor.authorBae, Soojeong C-
dc.contributor.authorChung, Ain-
dc.contributor.authorKim, Minue J-
dc.contributor.authorChang, Kee Hyun-
dc.contributor.authorRyu, Jeong-
dc.contributor.authorRenshaw, Perry F-
dc.contributor.authorLyoo, In Kyoon-
dc.date.accessioned2010-01-08T05:36:12Z-
dc.date.available2010-01-08T05:36:12Z-
dc.date.issued2007-01-03-
dc.identifier.citationNeuropsychobiology. 2006;54(2):120-5. Epub 2007 Jan 3.en
dc.identifier.issn0302-282X (Print)-
dc.identifier.urihttp://content.karger.com/produktedb/produkte.asp?typ=pdf&file=000098262-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17199097-
dc.identifier.urihttp://hdl.handle.net/10371/28929-
dc.description.abstractPreviously, our group reported the altered white matter tract integrity of the left anterior cingulate in posttraumatic stress disorder (PTSD) in whole-brain exploration. Current study intended to explore whether the alteration was more prominent in any specific regions of the cingulum bundle. Diffusion tensor images of 21 PTSD subjects and 21 healthy comparison subjects were acquired. Eight isocubic regions of interest (ROIs), i.e. bilateral rostral, subgenual, dorsal, and upper cingulum bundle, were selected. Fractional anisotropy values in each ROI, which indicate the white matter tract integrity, were measured and compared between groups. Relative to comparison subjects, PTSD subjects had significantly smaller fractional anisotropy values in the left side of rostral, subgenual and dorsal cingulum bundle (26.7, 25.0, 22.2% decrease, respectively), but not in the right side ROIs. We report an asymmetrical alteration of the cingulum bundle in PTSD.en
dc.language.isoenen
dc.publisherKargeren
dc.subjectAdulten
dc.subjectBrain Mappingen
dc.subjectCase-Control Studiesen
dc.subjectChi-Square Distributionen
dc.subjectDiffusion Magnetic Resonance Imagingen
dc.subjectFemaleen
dc.subjectGyrus Cinguli/*pathologyen
dc.subjectHumansen
dc.subjectMagnetic Resonance Imaging, Cineen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectStress Disorders, Post-Traumatic/*pathologyen
dc.titleAsymmetrically altered integrity of cingulum bundle in posttraumatic stress disorderen
dc.typeArticleen
dc.contributor.AlternativeAuthor김석주-
dc.contributor.AlternativeAuthor정도언-
dc.contributor.AlternativeAuthor심민영-
dc.contributor.AlternativeAuthor배수정-
dc.contributor.AlternativeAuthor장기현-
dc.contributor.AlternativeAuthor류정-
dc.contributor.AlternativeAuthor류인균-
dc.identifier.doi10.1159/000098262-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Psychiatry (정신과학전공)Journal Papers (저널논문_정신과학전공)
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