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Bronchial washing yield before and after forceps biopsy in patients with endoscopically visible lung cancers

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dc.contributor.authorLee, Hee Seok-
dc.contributor.authorKwon, Sung Youn-
dc.contributor.authorKim, Deog Kyeom-
dc.contributor.authorYoon, Ho Il-
dc.contributor.authorLee, Sang-Min-
dc.contributor.authorLee, Jae Ho-
dc.contributor.authorLee, Choon-Taek-
dc.contributor.authorChung, Hee Sun-
dc.contributor.authorHan, Sung Koo-
dc.contributor.authorShim, Young-Soo-
dc.contributor.authorYim, Jae Joon-
dc.date.accessioned2010-01-08T07:59:28Z-
dc.date.available2010-01-08T07:59:28Z-
dc.date.issued2007-02-15-
dc.identifier.citationRespirology. 2007 Mar;12(2):277-82.en
dc.identifier.issn1323-7799 (Print)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17298463-
dc.identifier.urihttps://hdl.handle.net/10371/29008-
dc.description.abstractBACKGROUND AND OBJECTIVE: The need for routine use of bronchial washing in addition to forceps biopsy has been debated in the diagnosis of endoscopically visible lung tumours. Moreover, the optimal sequence for obtaining bronchial washing and forceps biopsy specimens from endoscopically visible tumours through a flexible bronchoscope has not been well established. METHODS: A multicentre 13-month prospective randomized study was performed. Two hundred and thirty consecutive patients with endoscopically visible tumours were randomly assigned into a bronchial washing before forceps biopsy (pre-biopsy) group and a bronchial washing after forceps biopsy (post-biopsy) group. Bronchial washing and forceps biopsy were performed according to the assigned sequence. RESULTS: Two hundred and seven patients with a definite cytological or histological diagnosis of lung cancer were included in the analyses. One hundred and three were in the pre-biopsy group and 104 were in the post-biopsy group. The diagnostic yield of bronchial washing was 57.3% (59/103) in the pre-biopsy group and 55.8% (58/104) in the post-biopsy group (P = 0.88). In addition, bronchial washing provided the diagnosis in six patients without definite diagnosis from forceps biopsy, and its addition to forceps biopsy significantly increased the overall diagnostic yield of bronchoscopy from 93.7% to 96.6% (P = 0.03). CONCLUSION: The sequence for performing bronchial washing before or after forceps biopsy did not affect the diagnostic yield of bronchial washing in patients with endoscopically visible lung cancers. However, bronchial washing led to a significant increase in the overall diagnostic yield of bronchoscopy in patients with lung cancers.en
dc.language.isoenen
dc.publisherWiley-Blackwellen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectBiopsy/instrumentationen
dc.subjectBronchoalveolar Lavage/*methodsen
dc.subjectBronchoalveolar Lavage Fluid/*cytologyen
dc.subject*Bronchoscopyen
dc.subjectDiagnosis, Differentialen
dc.subjectFemaleen
dc.subjectFollow-Up Studiesen
dc.subjectHumansen
dc.subjectLung Neoplasms/*pathologyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectProspective Studiesen
dc.titleBronchial washing yield before and after forceps biopsy in patients with endoscopically visible lung cancersen
dc.typeArticleen
dc.contributor.AlternativeAuthor이희석-
dc.contributor.AlternativeAuthor권성연-
dc.contributor.AlternativeAuthor김덕겸-
dc.contributor.AlternativeAuthor윤호일-
dc.contributor.AlternativeAuthor이상민-
dc.contributor.AlternativeAuthor이재호-
dc.contributor.AlternativeAuthor이춘택-
dc.contributor.AlternativeAuthor정희선-
dc.contributor.AlternativeAuthor한성구-
dc.contributor.AlternativeAuthor심영수-
dc.contributor.AlternativeAuthor임재준-
dc.identifier.doi10.1111/j.1440-1843.2006.01001.x-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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