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Enhancement characteristics of cholangiocarcinomas on mutiphasic helical CT: emphasis on morphologic subtypes

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dc.contributor.authorKim, Na Ra-
dc.contributor.authorLee, Jeong Min-
dc.contributor.authorKim, Se Hyung-
dc.contributor.authorAn, Su Kyung-
dc.contributor.authorHan, Chang Jin-
dc.contributor.authorChoi, Seung Hong-
dc.contributor.authorHan, Joon Koo-
dc.contributor.authorLee, Hye Seung-
dc.contributor.authorJang, Ja Jun-
dc.contributor.authorChoi, Byung Ihn-
dc.date.accessioned2009-05-26T23:01:14Z-
dc.date.available2009-05-26T23:01:14Z-
dc.date.issued2008-03-06-
dc.identifier.citationClin Imaging 2008;32:114-20en
dc.identifier.issn0899-7071 (print)-
dc.identifier.issn1873-4499 (online)-
dc.identifier.urihttps://hdl.handle.net/10371/3861-
dc.description.abstractPURPOSE: The purpose of this study was to characterize the differences in CT enhancement pattern among the morphologic subtypes of cholangiocarcinomas.
MATERIALS AND METHODS: Unenhanced, hepatic arterial (HAP), and portal venous phase (PVP) CT images of 84 patients with pathologically proven cholangiocarcinoma were retrospectively reviewed. Tumors were of the following types: 27 mass-forming, 39 periductal-infiltrating, and 18 intraductal. The CT attenuation values of tumors were measured at each phase. The tumor enhancement ratio (ER) on HAP and PVP was calculated.
RESULTS: Each cholangiocarcinoma subtype produced characteristic enhancement relative to liver on HAP and PVP images: mass-forming tumors demonstrated hyperenhancing periphery and hyopenhancing centers; periductal-infiltrating tumors, hyperenhancing; and intraductal tumors, hypoenhancing. The ER of the tumor types was significantly different (P<.001, HAP, PVP): periductal-infiltrating tumors showed the highest ER (2.5; 3.8); the centers of mass-forming tumors, lowest (1.5; 2.2); the peripheries of mass-forming tumors, high (2.1; 3.0); intraductal tumors, low (1.9; 2.6).
CONCLUSION: Cholangiocarcinoma subtypes tended to exhibit distinct enhancement characteristics. Knowledge of these enhancement patterns may aid diagnosis and surgical planning.
en
dc.language.isoenen
dc.publisherElsevieren
dc.subjectCholangiocarcinomaen
dc.subjectCTen
dc.subjectEnhancement patternen
dc.titleEnhancement characteristics of cholangiocarcinomas on mutiphasic helical CT: emphasis on morphologic subtypesen
dc.typeArticleen
dc.contributor.AlternativeAuthor김나라-
dc.contributor.AlternativeAuthor이정민-
dc.contributor.AlternativeAuthor김세형-
dc.contributor.AlternativeAuthor안수경-
dc.contributor.AlternativeAuthor한창진-
dc.contributor.AlternativeAuthor최승홍-
dc.contributor.AlternativeAuthor한준구-
dc.contributor.AlternativeAuthor이혜승-
dc.contributor.AlternativeAuthor장자준-
dc.contributor.AlternativeAuthor최병인-
dc.identifier.doi10.1016/j.clinimag.2007.08.022-
dc.identifier.doi10.1016/j.clinimag.2007.08.022-
dc.citation.journaltitleClinical imaging-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Pathology (병리학전공)Journal Papers (저널논문_병리학전공)
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