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Clinicopathologic findings of colorectal traditional and sessile serrated adenomas in Korea: a multicenter study

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dc.contributor.authorLee, Sang Kil-
dc.contributor.authorChang, Hee Jin-
dc.contributor.authorKim, Tae Il-
dc.contributor.authorKim, Won Ho-
dc.contributor.authorPark, Choel Keun-
dc.contributor.authorChang, Dong Kyung-
dc.contributor.authorPark, Dong Il-
dc.contributor.authorSohn, Jin Hee-
dc.contributor.authorByeon, Jeong-Sik-
dc.contributor.authorYang, Suk-Kyun-
dc.contributor.authorKim, Jin Oh-
dc.contributor.authorLee, Suk-Ho-
dc.contributor.authorJin, So Young-
dc.contributor.authorPark, Cheol Hee-
dc.contributor.authorBaek, Il Hyun-
dc.contributor.authorEun, Chang Soo-
dc.contributor.authorHan, Dong Soo-
dc.contributor.authorPark, Seun Ja-
dc.contributor.authorChang, Hee Kyung-
dc.contributor.authorJeen, Yoon Tae-
dc.contributor.authorKim, Hyun Soo-
dc.contributor.authorPark, Dong Hoon-
dc.contributor.authorShin, Sung Jae-
dc.contributor.authorChang, Mee Soo-
dc.date.accessioned2009-05-27-
dc.date.available2009-05-27-
dc.date.issued2008-07-10-
dc.identifier.citationDigestion 2008;77:178-183en
dc.identifier.issn0012-2823 (print)-
dc.identifier.issn1421-9867 (online)-
dc.identifier.urihttp://www.karger.com/dig-
dc.identifier.urihttps://hdl.handle.net/10371/3873-
dc.descriptionCopyright © 2008 S. Karger AG, Baselen
dc.description.abstractBackground/Aims: Serrated polyps have emerged as important evidence supporting the serrated polyp-neoplasia pathway in colorectal carcinogenesis, an alternate to the classical adenoma-carcinoma sequence. However, there is confusion over the diagnostic criteria for serrated polyps including traditional serrated adenoma (TSA) and sessile serrated adenoma (SSA). In addition, clinical and pathologic characteristics of each are largely unknown and need further exploration. Methods: The 753 polyps that were previously diagnosed as serrated adenoma (SA) from 14 tertiary care university hospitals in Korea between 2003 and 2005 were evaluated for the clinicopathologic findings of TSA and SSA. Results: Among 753 cases, 420 (55.8%) were reclassified as TSA and 56 (7.4%) as SSA. Among the pathologic parameters, crypt branching, crypt dilatation, and horizontal crypts were more frequent in SSA than in TSA (p < 0.001). SSA was larger than TSA (12.6 +/- 7.3 vs. 9.8 +/- 6.9 mm, p = 0.005), was more likely to be flat type (p = 0.006), and was more frequently located in the proximal colorectum (p = 0.012). There were no significant differences in age, sex, and body mass index between TSA and SSA. Conclusions: Locationand endoscopic features of the polyps with abnormal crypt morphology in histologic findings could be helpful for the diagnosis and classification of SAs.en
dc.description.sponsorshipSupported by a research grant from the Korean Association for the Study of Intestinal Diseases (2006).en
dc.language.isoenen
dc.publisherKargeren
dc.subjectTraditional serrated adenomasen
dc.subjectSessile serrated adenomasen
dc.titleClinicopathologic findings of colorectal traditional and sessile serrated adenomas in Korea: a multicenter studyen
dc.typeArticleen
dc.contributor.AlternativeAuthor이상길-
dc.contributor.AlternativeAuthor장희진-
dc.contributor.AlternativeAuthor김태일-
dc.contributor.AlternativeAuthor김원호-
dc.contributor.AlternativeAuthor박철근-
dc.contributor.AlternativeAuthor장동경-
dc.contributor.AlternativeAuthor박동일-
dc.contributor.AlternativeAuthor소진희-
dc.contributor.AlternativeAuthor변정식-
dc.contributor.AlternativeAuthor양석균-
dc.contributor.AlternativeAuthor김진오-
dc.contributor.AlternativeAuthor이석호-
dc.contributor.AlternativeAuthor진소영-
dc.contributor.AlternativeAuthor박철희-
dc.contributor.AlternativeAuthor백일현-
dc.contributor.AlternativeAuthor은창수-
dc.contributor.AlternativeAuthor한동수-
dc.contributor.AlternativeAuthor박선자-
dc.contributor.AlternativeAuthor장희경-
dc.contributor.AlternativeAuthor진윤태-
dc.contributor.AlternativeAuthor김현수-
dc.contributor.AlternativeAuthor박동훈-
dc.contributor.AlternativeAuthor신성재-
dc.contributor.AlternativeAuthor장미수-
dc.identifier.doi10.1159/000142077-
dc.identifier.doi10.1159/000142077-
dc.citation.journaltitleDigestion-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Pathology (병리학전공)Journal Papers (저널논문_병리학전공)
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