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Clinical predictors of recurrent venous thromboembolism: a single institute experience in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Tae Min | - |
dc.contributor.author | Kim, Jin Soo | - |
dc.contributor.author | Han, Sae Won | - |
dc.contributor.author | Hong, Yong Sang | - |
dc.contributor.author | Kim, Inho | - |
dc.contributor.author | Ha, Jongwon | - |
dc.contributor.author | Kim, Sang Joon | - |
dc.contributor.author | Chung, Jin Wook | - |
dc.contributor.author | Park, Jae Hyung | - |
dc.contributor.author | Lee, Dongsoon | - |
dc.contributor.author | Park, Seonyang | - |
dc.contributor.author | Kim, Byoung Kook | - |
dc.contributor.author | Kim, Noe Kyeong | - |
dc.contributor.author | Yoon, Sung-Soo | - |
dc.date.accessioned | 2010-01-28T01:36:03Z | - |
dc.date.available | 2010-01-28T01:36:03Z | - |
dc.date.issued | 2008-06-27 | - |
dc.identifier.citation | Thromb Res. 2009;123(3):436-43. Epub 2008 Jun 24. | en |
dc.identifier.issn | 0049-3848 (Print) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18579181 | - |
dc.identifier.uri | http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6T1C-4SV12M8-3-5&_cdi=4887&_user=168665&_orig=search&_coverDate=01%2F31%2F2009&_sk=998769996&view=c&wchp=dGLbVzb-zSkzS&md5=2bdc07439dbc790dc3596a8c4e523f3f&ie=/sdarticle.pdf | - |
dc.identifier.uri | https://hdl.handle.net/10371/45975 | - |
dc.description.abstract | INTRODUCTION: Racial disparities in incidence rate as well as risk factors for venous thromboembolism (VTE) exist between Asian and Western populations. Moreover, predictors for recurrent VTE were not identified in Asians. Thus, this study was undertaken to investigate risk factors for recurrent VTE events in Korean people. MATERIALS AND METHODS: Three hundred-three patients newly diagnosed as VTE were enrolled from Seoul National University Hospital. Recurrence rate based on risk factors for VTE were investigated. Cumulative incidence of recurrent VTE was calculated by the Kaplan and Meier method. Independent predictors for VTE were determined using Cox proportional hazards model. RESULTS: After a median follow-up of 44 months, 24 (8%) of 303 patients relapsed for a total observation time of 1,217 patient-year. Cumulative incidences of recurrent VTE were 3% at 1 year, 10% at 5 years, and 18% at 8 years. Independent predictors for recurrent VTE were presence of residual thrombosis (hazard ratio [HR]=3.1, 95% confidence interval [CI] 1.0-9.3; p=0.044), antiphospholipid syndrome (APS) (HR=4.3, 95% CI 1.0-19.0; p=0.052), and age 50 years or younger (HR=2.5, 95% CI 1.0-6.6; p=0.053) by multivariate analysis. Residual thrombosis and APS remained predictive of recurrence by the anticoagulation-period stratified analysis. CONCLUSIONS: In contrast to Western populations, Korean patients with VTE had the lower recurrent rate. Extended anticoagulation is necessary for Korean patients with residual thrombosis or APS. | en |
dc.language.iso | en | en |
dc.publisher | Elsevier | en |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Aged, 80 and over | en |
dc.subject | Anticoagulants/therapeutic use | en |
dc.subject | Asian Continental Ancestry Group | en |
dc.subject | Child | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Kaplan-Meiers Estimate | en |
dc.subject | Korea/epidemiology | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Recurrence | en |
dc.subject | Risk Factors | en |
dc.subject | Thrombolytic Therapy | en |
dc.subject | Venous Thromboembolism/epidemiology/*etiology/therapy | en |
dc.subject | Young Adult | en |
dc.title | Clinical predictors of recurrent venous thromboembolism: a single institute experience in Korea | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 김태민 | - |
dc.contributor.AlternativeAuthor | 김진수 | - |
dc.contributor.AlternativeAuthor | 한새원 | - |
dc.contributor.AlternativeAuthor | 홍용상 | - |
dc.contributor.AlternativeAuthor | 김인호 | - |
dc.contributor.AlternativeAuthor | 하종원 | - |
dc.contributor.AlternativeAuthor | 김상준 | - |
dc.contributor.AlternativeAuthor | 정진욱 | - |
dc.contributor.AlternativeAuthor | 박재형 | - |
dc.contributor.AlternativeAuthor | 이동순 | - |
dc.contributor.AlternativeAuthor | 박선양 | - |
dc.contributor.AlternativeAuthor | 김병국 | - |
dc.contributor.AlternativeAuthor | 김노경 | - |
dc.contributor.AlternativeAuthor | 윤성수 | - |
dc.identifier.doi | 10.1016/j.thromres.2008.05.009 | - |
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