S-Space College of Dentistry/School of Dentistry (치과대학/치의학대학원) Dept. of Dentistry (치의학과) Journal Papers (저널논문_치의학과)
Enhanced fibronectin-mediated cell adhesion of human osteoblast by fibroblast growth factor, FGF-2
- Heo, Seong-Joo; Jang, Jun-Hyeog; Ku, Young; Chung, Chong-Pyoung
- Issue Date
- Springer Verlag
- Biotechnology Letters. 24: 1659-1663.
- Using specific recombinant human fibronectin peptide (hFNIII9-10) that contains the binding site for integrin, we found that the fibroblast growth factor, FGF-2, enhances fibronectin-mediated adhesion in human osteoblast-like MG63 cells. The mechanism of the synergistic adhesion was due to the activation of extracellular-regulated kinase (ERK)-type MAPK upon interaction of integrin to hFNIII9-10 and its downstream activation of signaling pathways.
- Files in This Item: There are no files associated with this item.