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Enhanced fibronectin-mediated cell adhesion of human osteoblast by fibroblast growth factor, FGF-2
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Heo, Seong-Joo | - |
dc.contributor.author | Jang, Jun-Hyeog | - |
dc.contributor.author | Ku, Young | - |
dc.contributor.author | Chung, Chong-Pyoung | - |
dc.date.accessioned | 2010-02-01T06:04:27Z | - |
dc.date.available | 2010-02-01T06:04:27Z | - |
dc.date.issued | 2002-10 | - |
dc.identifier.citation | Biotechnology Letters. 24: 1659-1663. | en |
dc.identifier.issn | 0141-5492 | - |
dc.identifier.uri | https://hdl.handle.net/10371/47283 | - |
dc.description.abstract | Using specific recombinant human fibronectin peptide (hFNIII9-10) that contains the binding site for integrin, we found that the fibroblast growth factor, FGF-2, enhances fibronectin-mediated adhesion in human osteoblast-like MG63 cells. The mechanism of the synergistic adhesion was due to the activation of extracellular-regulated kinase (ERK)-type MAPK upon interaction of integrin to hFNIII9-10 and its downstream activation of signaling pathways. | en |
dc.language.iso | en | en |
dc.publisher | Springer Verlag | en |
dc.subject | cell adhesion | en |
dc.subject | extracellular matrix | en |
dc.subject | FGF-2 | en |
dc.subject | fibronectin | en |
dc.subject | signal transduction | en |
dc.title | Enhanced fibronectin-mediated cell adhesion of human osteoblast by fibroblast growth factor, FGF-2 | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 허성주 | - |
dc.contributor.AlternativeAuthor | 장준혁 | - |
dc.contributor.AlternativeAuthor | 구영 | - |
dc.contributor.AlternativeAuthor | 정종평 | - |
dc.identifier.doi | 10.1023/A:1020617904251 | - |
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