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사람 치은 섬유아세포에서의 Tannerella forsythia 전세균, 막단백질, 당지질에 의한 염증성 사이토카인 발현
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김정은 | - |
dc.contributor.author | 이성훈 | - |
dc.contributor.author | 최봉규 | - |
dc.contributor.author | 구기태 | - |
dc.contributor.author | 김태일 | - |
dc.contributor.author | 이용무 | - |
dc.contributor.author | 구영 | - |
dc.contributor.author | 정종평 | - |
dc.contributor.author | 류인철 | - |
dc.date.accessioned | 2010-02-01T06:12:15Z | - |
dc.date.available | 2010-02-01T06:12:15Z | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | 대한치주과학회지 2008;38:543-550. | en |
dc.identifier.issn | 0250-3352 | - |
dc.identifier.uri | http://uci.or.kr/G100:I100-KOI(KISTI1.1003/JNL.JAKO200800557080899) | - |
dc.identifier.uri | https://hdl.handle.net/10371/47440 | - |
dc.description.abstract | Purpose: The purpose of this study was to investigate induction of cytokine expression in human gingival fibroblasts (HGFs) by whole cell and the components of T. forsythia. Material and Methods: After HGFs were treated with lipopolysaccharide (LPS), membrane protein isolated from T. forsythia or culture media of T. forsythia, the induction of interleukin (IL)-1, IL-6 and IL-8 was examined with real-time PCR and ELISA. Their induction ability of cytokines was compared with whole bacteria. Result: The expression of IL-6 and IL-8 was significantly induced in HGFs by whole bacteria and membrane protein. The expression of IL- was induced by membrane protein of T. forsythia, not by whole bacteria. LPS and condition media of T. forsythia slightly activated HGFs. Conclusion: The membrane protein of T. forsythia could be one of virulence factors. | en |
dc.language.iso | ko | en |
dc.publisher | 대한치주과학회 | en |
dc.subject | Tannerella forsythia | en |
dc.subject | virulence factors | en |
dc.subject | human gingival fibroblasts | en |
dc.title | 사람 치은 섬유아세포에서의 Tannerella forsythia 전세균, 막단백질, 당지질에 의한 염증성 사이토카인 발현 | en |
dc.type | Article | en |
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