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Poly(alpha-hydroxy acids) 제제 생분해성 차폐막의 치주조직 재생유도 능력에 관한 조직학적 장기 관찰

DC Field Value Language
dc.contributor.author류인철-
dc.contributor.author구영-
dc.contributor.author정종평-
dc.contributor.author한수부-
dc.contributor.author최상묵-
dc.date.accessioned2010-02-01T09:56:32Z-
dc.date.available2010-02-01T09:56:32Z-
dc.date.issued1997-
dc.identifier.citation대한치주과학회지 1997;27:.633-645en
dc.identifier.issn0250-3352-
dc.identifier.urihttp://uci.or.kr/G100:I100-KOI(KISTI1.1003/JNL.JAKO199721452720426)-
dc.identifier.urihttps://hdl.handle.net/10371/47901-
dc.description.abstractThe recent trend of research and development on guided tissue regeneration focuses on the biodegradable membranes, which eliminate the need for subsequent surgical removal. They have demonstrated significant and equivalent clinical improvements to the ePTFE membranes. This study evaluate guided tissue regeneration wound healing in surgically induced intrabony periodontal defects following surgical treatment with a synthetic biodegradable membranes, made from a copolymer of glycolide and lactide, in 8 beagle dogs. After full thickeness flap reflection, exposed buccal bone of maxillary and mandibular canine and premolar was removed surgically mesiodistally and occlusoapically at in size for preparation of periodontal defects. In experimental sites a customized barrier was formed and fitted to cover the defect. Flap was replaced slightly coronal to CEJ and sutured. Plaque control program was initiated and maintained until completion of the study. In 4, 8, 16 and 24 weeks after surgery, the animals were sacrificed and then undecalcified specimens were prepared for histologic evaluation. Histologic examination indicated significant periodontal regeneration characterized by new connective tissue attachment, cementum formation and bone formation. These membranes showed good biocompatibility throughout experiodontal period. The barriers had been completely resorbed with no apparent adverse effect on periodontal wound healing at 24 weeks. These results implicated that present synthetic biodegradable membrane facilitated guided tissue regeneration in periodontal defect.en
dc.description.sponsorship이 연구는 1996년도 서울대학교병원 임상공동연구비(1-96-75)의 지원에 의해 이루어졌습니다.en
dc.language.isokoen
dc.publisher대한치주과학회en
dc.subjectguided tissue regeneration:barrieren
dc.subjectsynthetic biodegradable membraneen
dc.subjectcopolymer of lactide and glycolideen
dc.subjectbiocompatibilityen
dc.subjectresorptionen
dc.subjectperiodontal defecten
dc.titlePoly(alpha-hydroxy acids) 제제 생분해성 차폐막의 치주조직 재생유도 능력에 관한 조직학적 장기 관찰en
dc.typeArticleen
Appears in Collections:
College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
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