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The Effect of pH on Na-Ca Exchange In Atrial Myocytes of Rabbit
토끼 심방근세포에서 pH가 Na-Ca 교환기전에 미치는 영향

DC Field Value Language
dc.contributor.authorSo, Insuk-
dc.contributor.authorEarm, Yung E-
dc.contributor.authorKim, Jun-
dc.contributor.authorHwang, Sang Ik-
dc.contributor.authorHo, Won Kyung-
dc.contributor.authorKim, Eui Yang-
dc.contributor.authorAhn, Cheal Soo-
dc.contributor.authorPark, Choon Ok-
dc.date.accessioned2009-07-14T22:43:45Z-
dc.date.available2009-07-14T22:43:45Z-
dc.date.issued1989-09-
dc.identifier.citationSeoul J Med, Vol.30 No.3, pp. 149-156-
dc.identifier.issn0582-6802-
dc.identifier.urihttps://hdl.handle.net/10371/5551-
dc.description.abstractIn atrial trabeculae and single atrial cells, we examined the effect of pH on the
Na-Ca exchange mechanism. In atrial trabeculae both acidic and alkaline pH reduced Na-free
contracture. Inward current of Na-Ca exchange activated by repolarizing pulse after a brief
depolarizing pulse to +40 mV for 2 ms from the holding potential of -70 mV in single atrial
cells was reduced by acidic pH, and enhanced by alkaline pH. Amiloride, which causes
intracellular acidosis, reduced Na-Ca exchange current and 20 mM NH4CI {intracellular
alkalosis}-enhanced Na-Ca exchange current. From the above results, it was concluded that
the effect of pH on forward and reverse modes of Na-Ca exchange might not be symmetric.
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dc.language.isoen-
dc.publisherSeoul National University College of Medicine-
dc.subjectNa-Ca exchange-
dc.subjectNa-free contracture-
dc.subjectpH-
dc.subjectRabbit atrium-
dc.titleThe Effect of pH on Na-Ca Exchange In Atrial Myocytes of Rabbit-
dc.title.alternative토끼 심방근세포에서 pH가 Na-Ca 교환기전에 미치는 영향-
dc.typeSNU Journal-
dc.contributor.AlternativeAuthor서인석-
dc.contributor.AlternativeAuthor엄융의-
dc.contributor.AlternativeAuthor김준-
dc.contributor.AlternativeAuthor황상익-
dc.contributor.AlternativeAuthor호원경-
dc.contributor.AlternativeAuthor김의용-
dc.contributor.AlternativeAuthor안철수-
dc.contributor.AlternativeAuthor박춘옥-
dc.citation.journaltitle서울 의대 잡지-
dc.citation.journaltitle서울 의대 학술지-
dc.citation.journaltitleSeoul Journal of Medicine-
dc.citation.endpage156-
dc.citation.number3-
dc.citation.pages149-156-
dc.citation.startpage149-
dc.citation.volume30-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 30 No.3 (1989)
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