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The Effect of pH on Na-Ca Exchange In Atrial Myocytes of Rabbit : 토끼 심방근세포에서 pH가 Na-Ca 교환기전에 미치는 영향
DC Field | Value | Language |
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dc.contributor.author | So, Insuk | - |
dc.contributor.author | Earm, Yung E | - |
dc.contributor.author | Kim, Jun | - |
dc.contributor.author | Hwang, Sang Ik | - |
dc.contributor.author | Ho, Won Kyung | - |
dc.contributor.author | Kim, Eui Yang | - |
dc.contributor.author | Ahn, Cheal Soo | - |
dc.contributor.author | Park, Choon Ok | - |
dc.date.accessioned | 2009-07-14T22:43:45Z | - |
dc.date.available | 2009-07-14T22:43:45Z | - |
dc.date.issued | 1989-09 | - |
dc.identifier.citation | Seoul J Med, Vol.30 No.3, pp. 149-156 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/5551 | - |
dc.description.abstract | In atrial trabeculae and single atrial cells, we examined the effect of pH on the
Na-Ca exchange mechanism. In atrial trabeculae both acidic and alkaline pH reduced Na-free contracture. Inward current of Na-Ca exchange activated by repolarizing pulse after a brief depolarizing pulse to +40 mV for 2 ms from the holding potential of -70 mV in single atrial cells was reduced by acidic pH, and enhanced by alkaline pH. Amiloride, which causes intracellular acidosis, reduced Na-Ca exchange current and 20 mM NH4CI {intracellular alkalosis}-enhanced Na-Ca exchange current. From the above results, it was concluded that the effect of pH on forward and reverse modes of Na-Ca exchange might not be symmetric. | - |
dc.language.iso | en | - |
dc.publisher | Seoul National University College of Medicine | - |
dc.subject | Na-Ca exchange | - |
dc.subject | Na-free contracture | - |
dc.subject | pH | - |
dc.subject | Rabbit atrium | - |
dc.title | The Effect of pH on Na-Ca Exchange In Atrial Myocytes of Rabbit | - |
dc.title.alternative | 토끼 심방근세포에서 pH가 Na-Ca 교환기전에 미치는 영향 | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | 서인석 | - |
dc.contributor.AlternativeAuthor | 엄융의 | - |
dc.contributor.AlternativeAuthor | 김준 | - |
dc.contributor.AlternativeAuthor | 황상익 | - |
dc.contributor.AlternativeAuthor | 호원경 | - |
dc.contributor.AlternativeAuthor | 김의용 | - |
dc.contributor.AlternativeAuthor | 안철수 | - |
dc.contributor.AlternativeAuthor | 박춘옥 | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 156 | - |
dc.citation.number | 3 | - |
dc.citation.pages | 149-156 | - |
dc.citation.startpage | 149 | - |
dc.citation.volume | 30 | - |
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