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High prevalence of hepatitis B virus infection in patients with B-cell non-Hodgkin's lymphoma in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Su Cheol | - |
dc.contributor.author | Jeong, Sook-Hyang | - |
dc.contributor.author | Kim, Jin | - |
dc.contributor.author | Han, Chul Ju | - |
dc.contributor.author | Kim, You Cheoul | - |
dc.contributor.author | Choi, Kui Sung | - |
dc.contributor.author | Cho, Jang Hyun | - |
dc.contributor.author | Lee, Myoungjin | - |
dc.contributor.author | Jung, Ha Hyun | - |
dc.contributor.author | Ki, Seung Seog | - |
dc.contributor.author | Chang, Yoon Hwan | - |
dc.contributor.author | Lee, Seung Sook | - |
dc.contributor.author | Park, Yeon Hee | - |
dc.contributor.author | Lee, Kee Ho | - |
dc.date.accessioned | 2010-03-31T05:37:06Z | - |
dc.date.available | 2010-03-31T05:37:06Z | - |
dc.date.issued | 2008-04-23 | - |
dc.identifier.citation | J Med Virol. 2008 ;80(6):960-6. | en |
dc.identifier.issn | 0146-6615 (Print) | - |
dc.identifier.uri | https://hdl.handle.net/10371/62199 | - |
dc.description.abstract | This study assessed the association of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection with non-Hodgkin's lymphoma in a highly HBV-endemic area. The prevalence of either HBV or HCV infection in 235 patients with non-Hodgkin's lymphoma was compared with that of an age- and sex-matched hospital control group of 235 patients. The prevalence of HBV infection was higher in B-cell non-Hodgkin's lymphoma (15.5%) than control (8.1%), but the prevalence of HCV infection in the non-Hodgkin's lymphoma patients (2.1%) and control group (3%) was similar. HBV prevalence increased significantly with age in the B-cell non-Hodgkin's lymphoma patients. The presence of HBV proteins and DNA in lymphoma tissues and peripheral blood mononuclear cells (PBMCs) from HBV-infected non-Hodgkin's lymphoma patients was also investigated using immunohistochemistry and PCR. HBV DNA was frequently detected in PBMCs from HBV-infected non-Hodgkin's lymphoma patients, but HBV antigens were not. Therefore, HBV infection, but not HCV infection, was associated with B-cell non-Hodgkin's lymphoma in Korea, suggesting a possible role for HBV in the development of non-Hodgkin's lymphoma. | en |
dc.language.iso | en | - |
dc.publisher | Wiley-Blackwell | en |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Aged, 80 and over | en |
dc.subject | Child | en |
dc.subject | Child, Preschool | en |
dc.subject | DNA, Viral/analysis | en |
dc.subject | Female | en |
dc.subject | Genes, Viral/genetics | en |
dc.subject | Hepatitis B/*complications/*epidemiology | en |
dc.subject | Hepatitis B Core Antigens/analysis | en |
dc.subject | Hepatitis B Surface Antigens/analysis | en |
dc.subject | Hepatitis B virus/genetics/isolation & purification | en |
dc.subject | Hepatitis C/epidemiology | en |
dc.subject | Humans | en |
dc.subject | Immunohistochemistry | en |
dc.subject | Korea/epidemiology | en |
dc.subject | Leukocytes, Mononuclear/virology | en |
dc.subject | Lymphoma, B-Cell/*complications/epidemiology/virology | en |
dc.subject | Lymphoma, Non-Hodgkin/*complications/epidemiology/virology | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Prevalence | en |
dc.subject | Stomach Neoplasms/complications/epidemiology | en |
dc.title | High prevalence of hepatitis B virus infection in patients with B-cell non-Hodgkin's lymphoma in Korea | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 박수철 | - |
dc.contributor.AlternativeAuthor | 정숙향 | - |
dc.contributor.AlternativeAuthor | 김진 | - |
dc.contributor.AlternativeAuthor | 한철주 | - |
dc.contributor.AlternativeAuthor | 김유철 | - |
dc.contributor.AlternativeAuthor | 최귀성 | - |
dc.contributor.AlternativeAuthor | 조장현 | - |
dc.contributor.AlternativeAuthor | 이명진 | - |
dc.contributor.AlternativeAuthor | 정하현 | - |
dc.contributor.AlternativeAuthor | 기승석 | - |
dc.contributor.AlternativeAuthor | 장윤환 | - |
dc.contributor.AlternativeAuthor | 이승숙 | - |
dc.contributor.AlternativeAuthor | 박연희 | - |
dc.contributor.AlternativeAuthor | 이기호 | - |
dc.identifier.doi | 10.1002/jmv.21168 | - |
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