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Diagnostic accuracy of multi-/single-detector row CT and contrast-enhanced MRI in the detection of hepatocellular carcinomas meeting the milan criteria before liver transplantation

Cited 33 time in Web of Science Cited 36 time in Scopus
Authors
Kim, Se Hyung; Choi, Byung Ihn; Lee, Jae Young; Kim, Soo Jin; So, Young Ho; Eun, Hyo Won; Lee, Jeong Min; Han, Joon Koo
Issue Date
2008-06-27
Publisher
Karger
Citation
Intervirology. 2008;51 Suppl 1:52-60.
Keywords
Carcinoma, Hepatocellular/*diagnosis/therapyContrast MediaFerric CompoundsGadoliniumHumansImage EnhancementImage Interpretation, Computer-AssistedLiver CirrhosisLiver Neoplasms/*diagnosis/therapy*Liver Transplantation*Magnetic Resonance Imaging/methodsSensitivity and Specificity*Tomography, X-Ray Computed/methods*Ultrasonography
Abstract
Liver transplantation has been considered to be the only causal treatment for liver cirrhosis patients with hepatocellular carcinoma (HCC) due to its theoretical advantage of eliminating both the tumor and liver disease. However, because of the shortage of donor organs, it is strongly recommended that liver transplantations should be performed on cirrhotic patients with HCCs only when the patients meet the predetermined criteria in terms of number and extent of HCCs. Imaging is thus decisive in the patient inclusion or exclusion from transplantation lists. The imaging techniques used are CT, MRI and ultrasonography. The latter has been proven to be ineffective for HCC surveillance in transplant recipients because of its heavy operator dependence and unreliable detection of small and intermediately sized HCCs. The purpose of this article, then, is to systematically review the diagnostic performances of single-/multidetector row CT, dynamic gadolinium-enhanced MRI, superparamagnetic iron oxide (SPIO)-enhanced MRI and double-contrast MRI using both gadolinium and SPIO for the detection of HCCs with special emphasis on liver transplantation.
ISSN
1423-0100 (Electronic)
Language
English
URI
http://hdl.handle.net/10371/62399
DOI
https://doi.org/10.1159/000122598
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College of Medicine/School of Medicine (의과대학/대학원)Radiology (영상의학전공)Journal Papers (저널논문_영상의학전공)
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