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Clinical features and outcome of solid pseudopapillary neoplasm: differences between adults and children
DC Field | Value | Language |
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dc.contributor.author | Lee, Seung Eun | - |
dc.contributor.author | Jang, Jin-Young | - |
dc.contributor.author | Hwang, Dae Wook | - |
dc.contributor.author | Park, Kwi-Won | - |
dc.contributor.author | Kim, Sun-Whe | - |
dc.date.accessioned | 2010-04-13T04:21:01Z | - |
dc.date.available | 2010-04-13T04:21:01Z | - |
dc.date.issued | 2008-12-17 | - |
dc.identifier.citation | Arch Surg. 2008 Dec;143(12):1218-21. | en |
dc.identifier.issn | 1538-3644 (Electronic) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19075175 | - |
dc.identifier.uri | http://archsurg.ama-assn.org/cgi/reprint/143/12/1218.pdf | - |
dc.identifier.uri | https://hdl.handle.net/10371/63076 | - |
dc.description.abstract | OBJECTIVES: To delineate the clinical and pathological characteristics of solid pseudopapillary neoplasm (SPN), compare them between adults and children, and determine the predictive features suggesting malignant potential. DESIGN: Retrospective analysis of patients who underwent surgery for a pathologically confirmed SPN. SETTING: Tertiary care referral center. PATIENTS: Sixty-two consecutive patients who underwent surgery for a pathologically confirmed SPN between 1985 and 2006. MAIN OUTCOME MEASURES: Demographic information and clinical presentation, radiological details, surgical data, pathological characteristics, postoperative course, and long-term survival. RESULTS: Among 62 patients, 47 patients were adults (mean age, 36 years; range, 18-63 years) and 15 patients were children (mean age, 12 years; range, 8-13 years). A palpable mass was the most common presenting symptom in children (9 of 15; 60%) and an incidentally detected pancreatic mass, in adults (18 of 47; 38.3%) (P = .001). The mean tumor size in children was significantly larger than in adults (8.0 vs 6.0 cm; P < .03). In children, the tumor was located in the head of the pancreas (10 of 15; 66.7%) and in adults, in the body or tail (38 of 47; 80.9%) (P = .001). Nine patients (14.5%) had malignant SPN. There was no significant clinical factor suggesting malignant potential. Two patients had a tumor recurrence. They were still alive after debulking surgery. There were no tumor-related deaths. CONCLUSION: Solid pseudopapillary neoplasm had different clinical features in adults and children. Because long-term survival can be achieved, even with the synchronous or metachronous metastatic lesions, SPN should be treated aggressively, with complete resection, even if this requires metastatectomy. | en |
dc.language.iso | en | en |
dc.publisher | American Medical Association | en |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | Carcinoma, Papillary/*diagnosis/mortality/pathology/*surgery | en |
dc.subject | Child | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Pancreatic Neoplasms/*diagnosis/mortality/pathology/*surgery | en |
dc.subject | Retrospective Studies | en |
dc.subject | Young Adult | en |
dc.title | Clinical features and outcome of solid pseudopapillary neoplasm: differences between adults and children | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 이승은 | - |
dc.contributor.AlternativeAuthor | 장진영 | - |
dc.contributor.AlternativeAuthor | 황대욱 | - |
dc.contributor.AlternativeAuthor | 박귀원 | - |
dc.contributor.AlternativeAuthor | 김선회 | - |
dc.identifier.doi | 10.1001/archsurg.143.12.1218 | - |
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