Meiotic Error of the Superovulated Oocytes In Mouse

Abstract

Chromosomes were studied in DBN2N mouse oocytes after superovulation. Twenty female mice were divided into 2 groups. Group I animals were induced to superovulate by injections of 5 IU PMSG and 5 IU hCG, and group II animals were injected with 10 IU PMSG and 10 IU hCG. Two cases of chiasma were found among the oocytes in group II. The rest of oocytes showed normal chromosomes in metaphase II. These results demonstrated that PMSG and hCG-induced superovulation correlated with chiasma formation.