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Carcinoembryonic Antigen (CEA) in N-methyl-N'-nitro-N-nitrosoguanidine-Induced Gastrointestinal Carcinomas of the Rats
N-methyl-N'-nitro-N-nitrosoguanidine 투여에 의한 실험적 상부 소화관 암종의 암태생항원 발현에 관한 면역조직화학적 관찰

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dc.contributor.authorKim, Woo Ho-
dc.contributor.authorKim, Yong Il-
dc.contributor.authorHan, Duck Jong-
dc.contributor.authorKim, Jin-Pok-
dc.date.accessioned2009-08-07T09:00:15Z-
dc.date.available2009-08-07T09:00:15Z-
dc.date.issued1987-12-
dc.identifier.citationSeoul J Med, Vol.28 No.4, pp. 297-301-
dc.identifier.issn0582-6802-
dc.identifier.urihttps://hdl.handle.net/10371/6552-
dc.description.abstractImmunohistologic findings on carcinoembryonic antigen (CEA) and its serum
level were compared in N-methyl-N' -nitro-N-nitrosoguanidine (MNNG)-induced gastrointestinal
malignant tumors. Of fifty-six malignant neoplastic lesions developed from 39 rats, only
10 carcinomas were CEA positive (10.7% of gastric and 31.8% of small intestinal cancers) in
cytoplasm of tumor cells by peroxidase-antiperoxidase (PAP) staining method. Animals with
CEA positive carcinoma showed the highest level of serum CEA than any other groups, but
the difference was not statistically significant (0.964 ± 0.150 versus 0.883 ±0.094). The
above findings lead to the suggestion that experimental gastric carcinoma expresses lower CEA
positivity than intestinal carcinoma, comparatively similar to the reported results in human
cases.
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dc.language.isoen-
dc.publisherSeoul National University College of Medicine-
dc.subjectN-methyl-N'-nitro-N-nitrosoguanidine-
dc.subjectExperimental carcinoma-
dc.subjectGastrointestinal carcinoma-
dc.subjectImmunohistologic carcinoembryonic antigen-
dc.titleCarcinoembryonic Antigen (CEA) in N-methyl-N'-nitro-N-nitrosoguanidine-Induced Gastrointestinal Carcinomas of the Rats-
dc.title.alternativeN-methyl-N'-nitro-N-nitrosoguanidine 투여에 의한 실험적 상부 소화관 암종의 암태생항원 발현에 관한 면역조직화학적 관찰-
dc.typeSNU Journal-
dc.contributor.AlternativeAuthor김우호-
dc.contributor.AlternativeAuthor김용일-
dc.contributor.AlternativeAuthor한덕종-
dc.contributor.AlternativeAuthor김진복-
dc.citation.journaltitle서울 의대 잡지-
dc.citation.journaltitle서울 의대 학술지-
dc.citation.journaltitleSeoul Journal of Medicine-
dc.citation.endpage301-
dc.citation.number4-
dc.citation.pages297-301-
dc.citation.startpage297-
dc.citation.volume28-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 28 No.4 (1987)
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