S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) The Seoul Journal of Medicine The Seoul Journal of Medicine Vol. 32 No.1 (1991)
Development of Polymer Prosthetic Heart Valve - Fabrication and In Vitro Test-
고분자 인공 심장판막의 개발 -제작과 성능실험
- Kim, In Young; Kim, Jong Won; Jung, Dae Young; Kim, Cheol Sang; Min, Byoung Goo
- Issue Date
- Seoul J Med, Vol.32 No.1, pp. 35-42
- Prosthetic heart valve; Hydrodynamic tester; Trileaflet polymer valve; Bileaflet polymer valve
- Prosthetic heart valves (PHV) with various types and materials have been
developed and used until now, but PHVs have various problems that need improving.
A new type of polymer PHV have been developed to ameliorate these problems. A
hydrodynamic tester has also been developed for the precise evaluation of hydrodynamic
performance of the developed PHV.
PHV are composed of polyurethane, a material commonly used in biomedical materials
because of its good biocompatibility and mechanical properties. To investigate
its hydrodynamic properties, a trileaflet and bileaflet type polymer valve was fabricated.
The results of comparative tests with the 2 polymer valves and a mechanical valve
showed that the trileaflet polymer valve had a better hydrodynamic performance than
the others. Though the bileaflet polymer valve showed a higher pressure drop and regurgitation
than the trileaflet valve due to thicker leaflet flection of the bileaflet valve,
if its fabrication method and design were corrected, a better result could be expected.
For a study of the long-term stability of the PHV, accelerated endurance tests and
stress analysis of PHVs are needed.