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Direct Effects of Amide-Type Local Anesthetics on Isolated Rat Ventricular Papillary Muscles : Lidocaine과 bupivacaine이 쥐의 좌심유두근에 미치는 직접적 효과에 관한 비교연구

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dc.contributor.authorLee, Sang Chul-
dc.date.accessioned2009-08-10-
dc.date.available2009-08-10-
dc.date.issued1991-06-
dc.identifier.citationSeoul J Med, Vol.32 No.2, pp. 83-90-
dc.identifier.issn0582-6802-
dc.identifier.urihttps://hdl.handle.net/10371/6732-
dc.description.abstractThe direct effects of 2 amide-type local anesthetics, lidocaine and bupivacaine,
on myocardial contractility were studied in isolated rat heart muscles. Three
different clinically equipotent doses of each agent were tested. In Tpd, +dp/dtmax,
and - dp/dt-,», the cardiodepressive action of lidocaine seemed to be slightly more
than that of bupivacaine, but bupivacaine showed a more depressive action on myocardial
contractility from the results of Tr and RT90%. We might say that lidocaine exhibit
significant cardiodepressive activity, which is at least similar with bupivacaine.
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dc.language.isoen-
dc.publisherSeoul National University College of Medicine-
dc.subjectAmide-
dc.subjectLocal Anesthetic-
dc.subjectLidocaine-
dc.subjectBupivacaine-
dc.subjectCardiodepression-
dc.titleDirect Effects of Amide-Type Local Anesthetics on Isolated Rat Ventricular Papillary Muscles-
dc.title.alternativeLidocaine과 bupivacaine이 쥐의 좌심유두근에 미치는 직접적 효과에 관한 비교연구-
dc.typeSNU Journal-
dc.contributor.AlternativeAuthor이상철-
dc.citation.journaltitle서울 의대 잡지-
dc.citation.journaltitle서울 의대 학술지-
dc.citation.journaltitleSeoul Journal of Medicine-
dc.citation.endpage90-
dc.citation.number2-
dc.citation.pages83-90-
dc.citation.startpage83-
dc.citation.volume32-
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