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Clinical and biochemical characteristics of polycystic ovary syndrome in Korean women
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chae, Soo Jin | - |
dc.contributor.author | Kim, Jin Ju | - |
dc.contributor.author | Choi, Young Min | - |
dc.contributor.author | Hwang, Kyu Ri | - |
dc.contributor.author | Jee, Byung Chul | - |
dc.contributor.author | Ku, Seung Yup | - |
dc.contributor.author | Suh, Chang Suk | - |
dc.contributor.author | Kim, Seok Hyun | - |
dc.contributor.author | Kim, Jung Gu | - |
dc.contributor.author | Moon, Shin Yong | - |
dc.date.accessioned | 2010-06-30T01:15:45Z | - |
dc.date.available | 2010-06-30T01:15:45Z | - |
dc.date.issued | 2008-06-27 | - |
dc.identifier.citation | Hum Reprod. 2008;23(8):1924-1931 | en |
dc.identifier.issn | 1460-2350 (Electronic) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18579512 | - |
dc.identifier.uri | http://humrep.oxfordjournals.org/cgi/reprint/23/8/1924.pdf | - |
dc.identifier.uri | https://hdl.handle.net/10371/68021 | - |
dc.description.abstract | BACKGROUND: We investigated the differences in anthropometrical, hormonal and insulin resistance parameters according to the subtype of polycystic ovary syndrome (PCOS) in Korean women. METHODS: We recruited 166 women with PCOS and retrospectively recruited 277 controls. PCOS was diagnosed by irregular menstruation (IM), polycystic ovary (PCO) and hyperandrogenism (HA). Subjects were divided into four subgroups: the IM/HA/PCO group (n = 87, 52.4%), the IM/PCO group (n = 52, 31.3%), the IM/HA group (n = 23, 13.9%) and the HA/PCO group (n = 4, 2.4%). Clinical and biochemical variables were compared among the PCOS subgroups. RESULTS: The IM/HA/PCO and IM/HA groups showed higher body mass index (P < 0.001) and waist-to-hip ratio (P < 0.001) than the IM/PCO group. The IM/HA group had higher triglyceride levels than the other groups (P < 0.001). Higher fasting insulin (P < 0.001) and postprandial 2 h insulin (P < 0.01) were noted in the IM/HA/PCO group and the IM/HA group, compared with the IM/PCO group. Women with PCOS showed lower sex hormone-binding globulin (P < 0.001) and higher systolic blood pressure (BP) (P = 0.004), diastolic BP (P = 0.001), fasting insulin (P < 0.001), postprandial 2 h insulin (P < 0.001), homeostatic model for insulin resistance (P < 0.001) and clinical and biochemical parameters of metabolic syndrome (P < 0.05) compared with subjects without PCOS. CONCLUSIONS: Women with PCOS without HA are common in Korea and are less likely to have metabolic dysfunction, insulin resistance and elevated BP. PCOS without HA may be a mild phenotype of PCOS. Therefore, women with PCOS in Korea could have a reduced likelihood of having metabolic syndrome compared with women of other ethnicities. | en |
dc.description.sponsorship | This study was supported by a grant (01-PJ10-PG6-01GN13-
0002) from the Korea Health 21 R&D Project, Ministry of Health and Welfare, Republic of Korea. | en |
dc.language.iso | en | en |
dc.publisher | Oxford University Press | en |
dc.subject | Adult | en |
dc.subject | Blood Pressure | en |
dc.subject | Body Mass Index | en |
dc.subject | Female | en |
dc.subject | Follicle Stimulating Hormone/blood | en |
dc.subject | Humans | en |
dc.subject | Hyperandrogenism/etiology | en |
dc.subject | Insulin/blood | en |
dc.subject | Insulin Resistance | en |
dc.subject | Korea/epidemiology | en |
dc.subject | Luteinizing Hormone/blood | en |
dc.subject | Menstruation Disturbances/etiology | en |
dc.subject | Metabolic Syndrome X/epidemiology | en |
dc.subject | Polycystic Ovary Syndrome/complications/*epidemiology/*physiopathology | en |
dc.subject | Prevalence | en |
dc.subject | Retrospective Studies | en |
dc.subject | Triglycerides/blood | en |
dc.title | Clinical and biochemical characteristics of polycystic ovary syndrome in Korean women | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 채수진 | - |
dc.contributor.AlternativeAuthor | 김진주 | - |
dc.contributor.AlternativeAuthor | 최영민 | - |
dc.contributor.AlternativeAuthor | 황규리 | - |
dc.contributor.AlternativeAuthor | 지병철 | - |
dc.contributor.AlternativeAuthor | 구승엽 | - |
dc.contributor.AlternativeAuthor | 서창석 | - |
dc.contributor.AlternativeAuthor | 김석현 | - |
dc.contributor.AlternativeAuthor | 김정구 | - |
dc.contributor.AlternativeAuthor | 문신용 | - |
dc.identifier.doi | 10.1093/humrep/den239 | - |
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