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Mycoplasma pneumoniae in Korean children: the epidemiology of pneumonia over an 18-year period

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dc.contributor.authorEun, Byung Wook-
dc.contributor.authorKim, Nam Hee-
dc.contributor.authorChoi, Eun Hwa-
dc.contributor.authorLee, Hoan Jong-
dc.date.accessioned2010-07-01T05:33:16Z-
dc.date.available2010-07-01T05:33:16Z-
dc.date.issued2008-04-19-
dc.identifier.citationJ Infect. 2008;56(5):326-331en
dc.identifier.issn1532-2742 (Electronic)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18420275-
dc.identifier.urihttp://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WJT-4S97J6W-1-7&_cdi=6887&_user=168665&_orig=search&_coverDate=05%2F31%2F2008&_sk=999439994&view=c&wchp=dGLzVtz-zSkWA&md5=139904a4b53afa941aaffa10d9c3baec&ie=/sdarticle.pdf-
dc.identifier.urihttps://hdl.handle.net/10371/68128-
dc.description.abstractOBJECTIVES: Mycoplasma pneumoniae (MP) is a major cause of community-acquired pneumonia in children. The aim of this study was to investigate the long-term epidemiology of MP pneumonia in Korean children. METHODS: A retrospective analysis of a database of 2405 patients with pneumonia at the Seoul National University Children's Hospital between 1986 and 2004 was performed. Serologic diagnosis for MP infection was made based on a 4-fold rise or single titers >/=1:640, which were measured by an indirect agglutination test. RESULTS: MP pneumonia was diagnosed in 568 patients over 18 years. The mean age was 5.7 years. Children younger than 5 years of age accounted for 44% of the cases. Six outbreaks were observed at intervals of 3-4 years. The earlier epidemics up until 1996 peaked in the summer, while the later epidemics peaked in the fall or early winter. Children <5 years old were more commonly affected during large epidemics compared to endemic periods. The geometric mean antibody titers were maintained >/=1:320 up to 7 months after the onset of illness. CONCLUSIONS: The results of this study revealed community outbreaks of MP pneumonia at 3-4-year intervals among Korean children. A significant proportion of young Korean children were affected by MP pneumonia, especially during large epidemics.en
dc.language.isoenen
dc.publisherElsevieren
dc.subjectAge Distributionen
dc.subjectAntibodies, Bacterial/blooden
dc.subjectChilden
dc.subjectChild, Preschoolen
dc.subject*Disease Outbreaksen
dc.subjectFemaleen
dc.subjectHospitals, Pediatricen
dc.subjectHospitals, Universityen
dc.subjectHumansen
dc.subjectInfanten
dc.subjectInfant, Newbornen
dc.subjectKorea/epidemiologyen
dc.subjectMaleen
dc.subjectMycoplasma pneumoniae/*immunologyen
dc.subjectPneumonia, Mycoplasma/*epidemiology/microbiologyen
dc.subjectTime Factorsen
dc.titleMycoplasma pneumoniae in Korean children: the epidemiology of pneumonia over an 18-year perioden
dc.typeArticleen
dc.contributor.AlternativeAuthor은병욱-
dc.contributor.AlternativeAuthor김남희-
dc.contributor.AlternativeAuthor최은화-
dc.contributor.AlternativeAuthor이환종-
dc.identifier.doi10.1016/j.jinf.2008.02.018-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Pediatrics (소아과학전공)Journal Papers (저널논문_소아과학전공)
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