지방모세포종(lipoblastoma) 2례

Abstract

Authors report two cases of localized type of lipoblastorna occurring in Korean infants, that were successfully treated by total excision. Case 1 was a 10 months old boy who came to the Hospital because of a recurrent inguinal mass that had been removed 5 months previously. The mass was firm and measured Gx 5 x 2cm. Elongated and lobulated masses wcre well encapsulated and delineatcd from the surrounding tissue, and showed light yellowish homogeneous cut surface with areas of rnyxoid change. The tumor mass was separated by irregular complete and incomplete septa. Case ~ was from a 3 months old girl who was found to have a mass in her upper back at the age of one month. This subcutaneous mass measured 2.5 X 2. G>: 2cm, and was elastic firm with mobility. It was well circumscribed from the surrounding tissue, and cut sections showed yellowish lobulated appearance. Microscopically both tumors were characterized by incomplete and complete lobules formed by crisscrossing bands of connective tissue. The tumor masses were composed of undifferentiated mesenchymal cells, fibroblasts, stellate cells as well as univacuolated and multi vacuolated fat cells. Areas of myxoid change were often seen in case 1. Mature fat cells wcre more abundant in the middle of the lobules, whereas the lipoblasts with rich vascularity were secn often around the fibrous septa. Although some neoplastic cells showed some nuclear hyperchrornasia no bizarre or giant cells were noted. Brief comments on age and site incidence, and management of this tumor were made.