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난소 과립막세포종의 병리학적 연구 : A Pathologic Study on Granulosa Cell Tumor of the Ovary
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 안선환 | - |
dc.contributor.author | 이상국 | - |
dc.contributor.author | 이진용 | - |
dc.contributor.author | 김승욱 | - |
dc.contributor.author | 장윤석 | - |
dc.date.accessioned | 2009-08-10T15:23:31Z | - |
dc.date.available | 2009-08-10T15:23:31Z | - |
dc.date.issued | 1983-06 | - |
dc.identifier.citation | Seoul J Med, Vol.24 No.3, pp. 281-289 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/6825 | - |
dc.description.abstract | One hundered and ninety-two cases cf ovarian
malignancy were reviewed over a period 0: 22 years from 1961 to 1982. Of these 13 cases :0.7?"· were classified as granulosa cell tumor. All tumors involved unilateral ovaries: right ovary, 6 cases; left, 6 cases; unstated side, 1 case. The mean age of patients in this series was 3~1. C years; the tumor was most frequent in the age group of 50 -59 years old. The frequency of nulliparity was 20%. Sixty percent of the patients were premenopausal women and 309£ were postmenopausal women. Clinically the commonest complaint by far was vaginal bleeding (53.9%). Abdominal mass or distention (46.2%) and abdominal pain (23.09'0) were also -cornmon symptoms. Physical examination usually .showed abdominal mass (46.2%) or abdominal distention (23.1%). The therapeutic regimens most commonly applied were unilateral salpingo-oophorectomy (46.296) or total hysterectomy with bilateral salpingo-oophorectomy (38.496). Pathologically the tumor was typically partly or predominently cystic with yellowish semisolid tumor tissue. Histopathologically several histologic patterns were observed in single tumor: the trabecularBllfe ), microfollicular (60%), and macrofollicular patterns (5096) were frequent growth patterns. Cystic endometrial hyperplasia was noted in 2590 of cases and -endometrial adenocarcinoma in 12.5%. All five patients on whom follow-up information is available were alive with no evidence of disease for 3. G years of average follow-up period. One case with granulosa cell tumor of diffuse pattern survived for 10 years. There were 2 cases of juvenile granulosa cell tumor. One case was a 1 year and ,) months old child -who presented vaginal bleeding, breast enlargement, clitoral enlargement, and pubic hairs. The ·other case was a 12 years old girl who presented Meigs' syndrome. Both tumors were cystic: one was partly cystic and partly solid and the other was predominently cystic. Microscopically classic pattern of juvenile granulosa cell tumor was noted: macrofollicular pattern (2 cases), diffuse pattern (I case), .diffuse luteinization (2 cases), and hyperchromatic nuclei (2 cases) were apparent. These two patients were alive without evidence of recurrence. | - |
dc.language.iso | ko | - |
dc.publisher | 서울대학교 의과대학 | - |
dc.title | 난소 과립막세포종의 병리학적 연구 | - |
dc.title.alternative | A Pathologic Study on Granulosa Cell Tumor of the Ovary | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | Ahn, Geung Hwan | - |
dc.contributor.AlternativeAuthor | Lee, Sang Kook | - |
dc.contributor.AlternativeAuthor | Lee, Jin Yong | - |
dc.contributor.AlternativeAuthor | Kim, Seung Wook | - |
dc.contributor.AlternativeAuthor | Chang, Yoon Seok | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 289 | - |
dc.citation.number | 3 | - |
dc.citation.pages | 281-289 | - |
dc.citation.startpage | 281 | - |
dc.citation.volume | 24 | - |
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