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Fibronectin fragment promotes osteoblast-associated gene expression and biological activity of human osteoblast-like cell
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ku, Young | - |
dc.contributor.author | Kim, Tae-Il | - |
dc.contributor.author | Jang, Jun-Hyeog | - |
dc.contributor.author | Chung, Chong-Pyoung | - |
dc.date.accessioned | 2010-07-12T05:01:00Z | - |
dc.date.available | 2010-07-12T05:01:00Z | - |
dc.date.issued | 2003-12 | - |
dc.identifier.citation | Biotechnology Letters 25:2007-2011. | en |
dc.identifier.issn | 0141-5492 | - |
dc.identifier.uri | 10.1023/B:BILE.0000004393.02839.d8 | - |
dc.identifier.uri | https://hdl.handle.net/10371/68590 | - |
dc.description.abstract | A fibronectin fragment, which spans from the ninth to tenth type III domain, showed >95% biological activity in promoting osteoblast adhesion, proliferation and differentiation level compared with those of native fibronectin (FN) molecule. This suggests that the FN type III ninth-tenth domain fragment serves a good substitute for native FN in biomimetic application for osteogenesis. | en |
dc.description.sponsorship | This study was supported by a grant from the Korean
Science and Engineering Foundation through the Intellectual Biointerface Engineering Center at Seoul National University. | en |
dc.language.iso | en | en |
dc.publisher | Springer Verlag | en |
dc.subject | alkaline phosphatase | en |
dc.subject | extracellular matrix | en |
dc.subject | fibronectin | en |
dc.subject | gene expression | en |
dc.subject | osteoblast | en |
dc.title | Fibronectin fragment promotes osteoblast-associated gene expression and biological activity of human osteoblast-like cell | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 구영 | - |
dc.contributor.AlternativeAuthor | 김태일 | - |
dc.contributor.AlternativeAuthor | 장준혁 | - |
dc.contributor.AlternativeAuthor | 정종평 | - |
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