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Recent Korean isolates of duck hepatitis virus reveal the presence of a new geno- and serotype when compared to duck hepatitis virus type 1 type strains

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dc.contributor.authorKim, M.-C.-
dc.contributor.authorKwon, Y.-K.-
dc.contributor.authorJoh, S.-J.-
dc.contributor.authorKim, S.-J.-
dc.contributor.authorTolf, C.-
dc.contributor.authorKim, J.-H.-
dc.contributor.authorSung, H.-W.-
dc.contributor.authorLindberg, A. M.-
dc.contributor.authorKwon, J.-H.-
dc.date.accessioned2009-08-11T23:15:58Z-
dc.date.available2009-08-11T23:15:58Z-
dc.date.issued2007-08-10-
dc.identifier.citationArch Virol 152: 2059-2072en
dc.identifier.issn0304-8608 (print)-
dc.identifier.issn1432-8798 (online)-
dc.identifier.urihttp://hdl.handle.net/10371/6983-
dc.description.abstractDuck hepatitis was first reported in 1985 in Korea. The complete nucleotide sequence of two past Korean isolates, DHV-HS and DHV-HSS, isolated in 1994 and 1995, and four recent Korean isolates, AP-03337, AP-04009, AP-04114 and AP-04203 isolated in 2003 and 2004, were determined. Phylogenetic analysis using the 3D protein sequence confirmed that the previously characterized duck hepatitis virus type 1 strains and the six Korean isolates described here constitute a monophyletic group and form two clades/genotypes in which all except the four recent Korean isolates form one group (A) and the recent Korean isolates of 2003 and 2004 constitute a second group (B). Phylogenetic analysis of the VP1 protein supported the division into two different groups. Antisera raised against viruses of group A showed significant neutralizing cross-reaction against a member of the same genotype but not to a strain of group B and vice versa. These results demonstrated that the two genotypes also could be regarded as two different serotypes.en
dc.description.sponsorshipThe authors would like to thank Hyuk-Man Kwon for propagation
of duck hepatitis virus. This work was supported
financially by the National Veterinary Research and Quarantine
Service (NVRQS), Ministry of Agricultural and Forestry
(MAF), Republic of Korea. AML and CT were supported by
the Knowledge Foundation, Sweden, and the Research Programme
in Medical Bioinformatics, Karolinska Institute,
Stockholm, Sweden
en
dc.language.isoen-
dc.publisherSpringer Verlagen
dc.titleRecent Korean isolates of duck hepatitis virus reveal the presence of a new geno- and serotype when compared to duck hepatitis virus type 1 type strainsen
dc.typeArticleen
dc.contributor.AlternativeAuthor김재홍-
dc.identifier.doi10.1007/s00705-007-1023-0-
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College of Veterinary Medicine (수의과대학)Dept. of Veterinary Medicine (수의학과)Journal Papers (저널논문_수의학과)
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