방광암의 병태학적 연구

Abstract

A histo-topographic technic for the investigation of urotheIiaI lesions adjacent to the carcinoma of urinary bladder is developed, and details of its procedure are described. The advantages of applying this technic include the followings: I. To identify the selection of surgical procedure in regard to patient's prognostic factors. 2. To provide basic informations on the determination of safety margin by demonstration of incipient lesions such as in situ carcinoma or dysplasra, 3. To postulate the oncogenic relationship with von Brunn's nest, cystitis cystica, polypoid cystitis and squamous metaplasia, and 4. To upgrade the cystoscopic biopsy technic and its interpretation. The major technical concern in this procedure is the elimination of artificial trauma for the preservation of urothelial mucosa.