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Performance testing of several classifiers for differentiating obstructive lung diseases based on texture analysis at high-resolution computerized tomography (HRCT)
Cited 24 time in
Web of Science
Cited 31 time in Scopus
- Authors
- Issue Date
- 2009-01
- Publisher
- Elsevier
- Citation
- Computer Methods and Programs in Biomedicine 93 (2009) 206-215
- Keywords
- Bayesian classifier ; ANN (artificial neural net) ; SVM (support vector machine) ; Obstructive lung disease ; Texture analysis
- Abstract
- Machine classifiers have been used to automate quantitative analysis and avoid intra–interreader
variability in previous studies. The selection of an appropriate classification schemeis
important for improving performance based on the characteristics of the data set. This paper
investigated the performance of several machine classifiers for differentiating obstructive
lung diseases using texture analysis on various ROI (region of interest) sizes. 265 highresolution
computerized tomography (HRCT) images were taken from 92 subjects. On each
image, two experienced radiologists selected ROIs with various sizes representing area of
severe centrilobular emphysema (PLE, n = 63), mild centrilobular emphysema (CLE, n = 65),
bronchiolitis obliterans (BO, n = 70) or normal lung (NL, n = 67). Four machine classifiers were
implemented: naïve Bayesian classifier, Bayesian classifier, ANN (artificial neural net) and
SVM (support vector machine). For a testing method, 5-fold cross-validation methods were
used and each validation was repeated 20 times. The SVM had the best performance in
overall accuracy (in ROI size of 32×32 and 64×64) (t-test, p < 0.05). There was no significant
overall accuracy difference between Bayesian and ANN (t-test, p < 0.05). The naïve
Bayesian method performed significantly worse than the other classifiers (t-test, p < 0.05).
SVM showed the best performance for classification of the obstructive lung diseases in this
study.
- ISSN
- 0169-2607
- Language
- English
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