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Lower bone mineral density is associated with higher coronary calcification and coronary plaque burdens by multidetector row coronary computed tomography in pre- and postmenopausal women

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dc.contributor.authorChoi, Sung Hee-
dc.contributor.authorAn, Jee Hyun-
dc.contributor.authorLim, Soo-
dc.contributor.authorKoo, Bo Kyung-
dc.contributor.authorChang, Hyuck Jae-
dc.contributor.authorPark, Young Joo-
dc.contributor.authorJang, Hak Chul-
dc.contributor.authorShin, Chan Soo-
dc.contributor.authorPark, Kyong Soo-
dc.contributor.authorChoi, Sang Il-
dc.contributor.authorPark, Se Eun-
dc.date.accessioned2012-05-24T06:20:33Z-
dc.date.available2012-05-24T06:20:33Z-
dc.date.issued2009-11-
dc.identifier.citationCLINICAL ENDOCRINOLOGY; Vol.71 5; 644-651ko_KR
dc.identifier.issn0300-0664-
dc.identifier.urihttps://hdl.handle.net/10371/76421-
dc.description.abstractP>Objectives There is growing evidence for the association between bone mineral density (BMD) and vascular calcification, which is related to cardiovascular disease. Coronary multidetector row computed tomography (MDCT) is a noninvasive tool developed to evaluate coronary status precisely. We used MDCT to evaluate this association. Design and patients Eight hundred and fifteen subjects received routine checkups. After excluding subjects with factors affecting bone metabolism and cardiovascular disease, 467 subjects were analysed. Measurements Coronary calcification was measured with MDCT and BMD was measured with dual X-ray absorptiometry (DXA). Results The BMD of the femur and the lumbar spine (L-spine) were negatively associated with the coronary calcium score (CCS) after adjusting for age in women but not in men. This inverse correlation was stronger in women with a longer time since menopause (r = -0 center dot 35 at femur, postmenopausal women vs. r = -0 center dot 10 at femur, premenopausal women, P < 0 center dot 05), and it was stronger at the femur than in the L-spine (r = -0 center dot 35 at femur vs. r = -0 center dot 16 at L-spine, P < 0 center dot 01). The relationship was also stronger in postmenopausal women with osteoporosis and osteopaenia than in women with normal BMD. The lower BMD was associated with higher coronary plaque burdens and multidiseased coronary vessels in both men and women (P < 0 center dot 01). Conclusions Increased CCS and subclinical atherosclerosis of plaque burdens as revealed by MDCT was associated with a low BMD in all women, independent of cardiovascular risk factors and age.ko_KR
dc.language.isoenko_KR
dc.publisherWILEY-BLACKWELL PUBLISHING, INCko_KR
dc.titleLower bone mineral density is associated with higher coronary calcification and coronary plaque burdens by multidetector row coronary computed tomography in pre- and postmenopausal womenko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor최성희-
dc.contributor.AlternativeAuthor안지현-
dc.contributor.AlternativeAuthor임수-
dc.contributor.AlternativeAuthor구보경-
dc.contributor.AlternativeAuthor박세은-
dc.contributor.AlternativeAuthor장혁재-
dc.contributor.AlternativeAuthor최상일-
dc.contributor.AlternativeAuthor박영주-
dc.contributor.AlternativeAuthor박경수-
dc.contributor.AlternativeAuthor장학철-
dc.contributor.AlternativeAuthor신찬수-
dc.identifier.doi10.1111/j.1365-2265.2009.03535.x-
dc.citation.journaltitleCLINICAL ENDOCRINOLOGY-
dc.description.citedreferenceDetrano R, 2008, NEW ENGL J MED, V358, P1336, DOI 10.1056/NEJMoa072100-
dc.description.citedreferencePundziute G, 2007, DIABETES CARE, V30, P1113, DOI 10.2337/dc06-2104-
dc.description.citedreferenceShen H, 2007, CALCIFIED TISSUE INT, V80, P244, DOI 10.1007/s00223-007-9006-4-
dc.description.citedreferenceHofbauer LC, 2007, OSTEOPOROSIS INT, V18, P251, DOI 10.1007/s00198-006-0282-z-
dc.description.citedreferenceJorgensen L, 2006, CALCIFIED TISSUE INT, V79, P207, DOI 10.1007/s00223-006-0071-x-
dc.description.citedreferenceFarhat GN, 2006, CALCIFIED TISSUE INT, V79, P102, DOI 10.1007/s00223-006-0052-0-
dc.description.citedreferenceBagger YZ, 2006, J INTERN MED, V259, P598, DOI 10.1111/j.1365-2796.2006.01640.x-
dc.description.citedreferenceSinnott B, 2006, CALCIFIED TISSUE INT, V78, P195, DOI 10.1007/s00223-005-0244-z-
dc.description.citedreferenceLeber AW, 2006, J AM COLL CARDIOL, V47, P672, DOI 10.1016/j.jacc.2005.10.058-
dc.description.citedreferenceTowler DA, 2006, ANN NY ACAD SCI, V1068, P327, DOI 10.1196/annals.1346.036-
dc.description.citedreferenceRaff GL, 2005, J AM COLL CARDIOL, V46, P552, DOI 10.1016/j.jacc.2005.05.056-
dc.description.citedreferenceDavies MR, 2005, J AM SOC NEPHROL, V16, P917-
dc.description.citedreferenceJorgensen L, 2004, AM J EPIDEMIOL, V160, P549, DOI 10.1093/aje/kwh252-
dc.description.citedreferenceSchulz E, 2004, J CLIN ENDOCR METAB, V89, P4246, DOI 10.1210/jc.2003-030964-
dc.description.citedreferenceLondon GM, 2004, J AM SOC NEPHROL, V15, P1943, DOI 10.1097/01.asn.0000129337.50739.48-
dc.description.citedreferenceLeber AW, 2004, J AM COLL CARDIOL, V43, P1241, DOI 10.1016/j.jacc.2003.10.059-
dc.description.citedreferenceShao JS, 2003, J BIOL CHEM, V278, P50195, DOI 10.1074/jbc.M308825200-
dc.description.citedreferenceSchafer C, 2003, J CLIN INVEST, V112, P357, DOI 10.1172/JCI200317202-
dc.description.citedreferenceTanko LB, 2003, CALCIFIED TISSUE INT, V73, P15, DOI 10.1007/s00223-002-2070-x-
dc.description.citedreferenceLeber AW, 2003, AM J CARDIOL, V91, P714, DOI 10.1016/S0002-9149(02)03411-2-
dc.description.citedreferenceSpeer MY, 2002, J EXP MED, V196, P1047, DOI 10.1084/jem.20020911-
dc.description.citedreferenceDemer LL, 2002, INT J EPIDEMIOL, V31, P737-
dc.description.citedreferencevan der Klift M, 2002, CALCIFIED TISSUE INT, V70, P443, DOI 10.1007/s00223-001-2076-9-
dc.description.citedreferenceChristian RC, 2002, J CLIN ENDOCR METAB, V87, P1062-
dc.description.citedreferenceVIRMANI R, 2002, J INTERV CARDIOL, V15, P439-
dc.description.citedreferenceKiel DP, 2001, CALCIFIED TISSUE INT, V68, P271-
dc.description.citedreferenceSchroeder S, 2001, J AM COLL CARDIOL, V37, P1430-
dc.description.citedreferenceJorgensen L, 2001, STROKE, V32, P47-
dc.description.citedreferenceKado DM, 2000, J BONE MINER RES, V15, P1974-
dc.description.citedreferenceYoshitake H, 1999, P NATL ACAD SCI USA, V96, P8156-
dc.description.citedreferencevon der Recke P, 1999, AM J MED, V106, P273-
dc.description.citedreferenceBucay N, 1998, GENE DEV, V12, P1260-
dc.description.citedreferenceVirmani R, 1998, EUR HEART J, V19, P678-
dc.description.citedreferenceBarengolts EI, 1998, CALCIFIED TISSUE INT, V62, P209-
dc.description.citedreferenceWatson KE, 1997, CIRCULATION, V96, P1755-
dc.description.citedreferenceUyama O, 1997, STROKE, V28, P1730-
dc.description.citedreferenceParhami F, 1997, ARTERIOSCL THROM VAS, V17, P680-
dc.description.citedreferenceKURO OM, 1997, NATURE, V390, P45-
dc.description.citedreferenceJie KSG, 1996, CALCIFIED TISSUE INT, V59, P352-
dc.description.citedreferenceBROWNER WS, 1993, STROKE, V24, P940-
dc.description.citedreferenceBROWNER WS, 1991, LANCET, V338, P355-
dc.description.citedreferenceKRAGEL AH, 1989, CIRCULATION, V80, P1747-
dc.description.tc6-
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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