Publications
Detailed Information
Prognostic Factors Affecting the Outcome of Salvage Radiotherapy for Isolated Locoregional Recurrence After Mastectomy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Kyubo | - |
dc.contributor.author | Chie, Eui Kyu | - |
dc.contributor.author | Han, Wonshik | - |
dc.contributor.author | Noh, Dong-Young | - |
dc.contributor.author | Oh, Do-Youn | - |
dc.contributor.author | Im, Seock-Ah | - |
dc.contributor.author | Kim, Tae-You | - |
dc.contributor.author | Bang, Yung-Jue | - |
dc.contributor.author | Ha, Sung W. | - |
dc.date.accessioned | 2012-05-29T09:00:56Z | - |
dc.date.available | 2012-05-29T09:00:56Z | - |
dc.date.created | 2020-12-21 | - |
dc.date.created | 2020-12-21 | - |
dc.date.issued | 2010-02 | - |
dc.identifier.citation | American Journal of Clinical Oncology, Vol.33 No.1, pp.23-27 | - |
dc.identifier.issn | 0277-3732 | - |
dc.identifier.other | 119302 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76578 | - |
dc.description.abstract | Objectives: To evaluate the prognostic factors affecting the outcome of salvage radiotherapy for isolated locoregional recurrence after mastectomy. Methods: Between May 1988 and April 2002, 65 breast cancer patients Underwent radiotherapy as a component of salvage treatment for isolated locoregional recurrence after mastectomy. The sites Of failure were as follows: chest wall in 37 patients, regional lymph nodes (LNs) in 23 patients, and combined chest wall and LNs in 5 patients. None of the patients had previously been treated with radiation. Thirty-nine patients had surgical resection, and 55 patients received systemic chemotherapy and/or hormonal therapy for recurrent disease. In 51 cases (78.5%), the chest wall and ipsilateral regional lymphatics including supraclavicular, axillary, and internal mammary LNs were irradiated. Median close was 50.4 Gy (range: 50-71.5). Median duration of follow-up was 52 months (range: 2-206). Results: The 5-year overall survival rate was 48.1%. On multivariate analysis, patients without initial nodal involvement had better overall survival (P = 0.0118). The 5-year locoregional progress ion-free survival rate was 69.8%, and time to recurrence (>36 months vs <= 36 months) had an influence on the outcome with borderline significance (P = 0.0775). The 5-year distant metastasis-free survival rate was 42.1%. Lack of systemic therapy alter recurrence (P = 0.0089) and age <50 years at recurrence (P = 0.0145) were significant prognostic factors predicting poor distant metastasis-free survival. Conclusions: Radiotherapy for isolated locoregional relapse after inastectomy achieved locoregional control in about two-thirds of patients. Major pattern Of failure was distant relapse, and systemic therapy is warranted to prevent secondary dissemination. | - |
dc.language | 영어 | - |
dc.language.iso | en | ko_KR |
dc.publisher | Lippincott Williams & Wilkins Ltd. | - |
dc.title | Prognostic Factors Affecting the Outcome of Salvage Radiotherapy for Isolated Locoregional Recurrence After Mastectomy | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 임석아 | - |
dc.identifier.doi | 10.1097/COC.0b013e31819e2c02 | - |
dc.citation.journaltitle | American Journal of Clinical Oncology | - |
dc.description.citedreference | Wapnir IL, 2008, CLIN BREAST CANCER, V8, P287, DOI 10.3816/CBC.2008.n.035 | - |
dc.description.citedreference | De Laurentiis M, 2008, J CLIN ONCOL, V26, P44, DOI 10.1200/JCO.2007.11.3787 | - |
dc.description.citedreference | Carreno G, 2007, BREAST CANCER RES TR, V102, P61, DOI 10.1007/s10549-006-9310-0 | - |
dc.description.citedreference | Jagsi R, 2005, INT J RADIAT ONCOL, V62, P1035, DOI 10.1016/j.ijrobp.2004.12.014 | - |
dc.description.citedreference | Truong PT, 2005, INT J RADIAT ONCOL, V62, P175, DOI 10.1016/j.ijrobp.2004.09.013 | - |
dc.description.citedreference | Truong PT, 2005, INT J RADIAT ONCOL, V61, P1337, DOI 10.1016/j.ijrobp.2004.08.009 | - |
dc.description.citedreference | Bellon JR, 2005, J CLIN ONCOL, V23, P1934, DOI 10.1200/JCO.2005.04.032 | - |
dc.description.citedreference | Haffty BG, 2004, CANCER, V100, P252, DOI 10.1002/cncr.11915 | - |
dc.description.citedreference | Chagpar A, 2003, ANN SURG ONCOL, V10, P628, DOI 10.1245/ASO.2003.01.004 | - |
dc.description.citedreference | Martin M, 2003, ANN ONCOL, V14, P833, DOI 10.1093/annonc/mdg260 | - |
dc.description.citedreference | Schuck A, 2002, BRIT J RADIOL, V75, P663 | - |
dc.description.citedreference | Cheng JCH, 2002, INT J RADIAT ONCOL, V52, P980 | - |
dc.description.citedreference | *AJCC, 2002, AJCC CANC STAG MAN | - |
dc.description.citedreference | Eifel P, 2001, J NATL CANCER I, V93, P979 | - |
dc.description.citedreference | RAUSCHECKER H, 2001, COCHRANE DB SYST REV, V4, P2195 | - |
dc.description.citedreference | Freedman GM, 2000, ONCOLOGY-NY, V14, P1561 | - |
dc.description.citedreference | Deutsch M, 2000, AM J CLIN ONCOL-CANC, V23, P494 | - |
dc.description.citedreference | Haylock BJ, 2000, INT J RADIAT ONCOL, V46, P355 | - |
dc.description.citedreference | Hsi RA, 1998, INT J RADIAT ONCOL, V42, P495 | - |
dc.description.citedreference | Willner J, 1997, INT J RADIAT ONCOL, V37, P853 | - |
dc.description.citedreference | Recht A, 1996, NEW ENGL J MED, V334, P1356 | - |
dc.description.citedreference | BORNER M, 1994, J CLIN ONCOL, V12, P2071 | - |
dc.description.citedreference | SCHWAIBOLD F, 1991, INT J RADIAT ONCOL, V21, P299 | - |
dc.description.citedreference | HALVERSON KJ, 1990, INT J RADIAT ONCOL, V19, P851 | - |
dc.description.citedreference | ABERIZK WJ, 1986, CANCER, V58, P1214 | - |
dc.description.citedreference | BEDWINEK JM, 1981, INT J RADIAT ONCOL, V7, P581 | - |
dc.description.citedreference | *NCCN, NCCN PRACT GUID ONC | - |
dc.description.tc | 0 | - |
dc.identifier.wosid | 000274413500004 | - |
dc.identifier.scopusid | 2-s2.0-76749133184 | - |
dc.citation.endpage | 27 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 23 | - |
dc.citation.volume | 33 | - |
dc.identifier.sci | 000274413500004 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Chie, Eui Kyu | - |
dc.contributor.affiliatedAuthor | Han, Wonshik | - |
dc.contributor.affiliatedAuthor | Noh, Dong-Young | - |
dc.contributor.affiliatedAuthor | Oh, Do-Youn | - |
dc.contributor.affiliatedAuthor | Im, Seock-Ah | - |
dc.contributor.affiliatedAuthor | Kim, Tae-You | - |
dc.contributor.affiliatedAuthor | Bang, Yung-Jue | - |
dc.contributor.affiliatedAuthor | Ha, Sung W. | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | LOCAL-REGIONAL RECURRENCE | - |
dc.subject.keywordPlus | CHEST-WALL RECURRENCE | - |
dc.subject.keywordPlus | CANCER FOLLOWING MASTECTOMY | - |
dc.subject.keywordPlus | STAGE BREAST-CANCER | - |
dc.subject.keywordPlus | RADIATION-THERAPY | - |
dc.subject.keywordPlus | ADJUVANT CHEMOTHERAPY | - |
dc.subject.keywordPlus | FAILURE | - |
dc.subject.keywordPlus | SURGERY | - |
dc.subject.keywordPlus | ALWAYS | - |
dc.subject.keywordPlus | T1-T2 | - |
dc.subject.keywordAuthor | breast cancer | - |
dc.subject.keywordAuthor | locoregional recurrence | - |
dc.subject.keywordAuthor | mastectomy | - |
dc.subject.keywordAuthor | radiotherapy | - |
dc.subject.keywordAuthor | systemic therapy | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.