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Assessment of haemodynamic effects of surgical correction for severe functional tricuspid regurgitation: cardiac magnetic resonance imaging study
DC Field | Value | Language |
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dc.contributor.author | Kim, Hyung-Kwan | - |
dc.contributor.author | Kim, Yong-Jin | - |
dc.contributor.author | Park, Eun-Ah | - |
dc.contributor.author | Bae, Ji-Seon | - |
dc.contributor.author | Kim, Kyung-Hwan | - |
dc.contributor.author | Sohn, Dae-Won | - |
dc.contributor.author | Park, Jae-Hyung | - |
dc.contributor.author | Park, Young-Bae | - |
dc.contributor.author | Ahn, Hyuk | - |
dc.contributor.author | Kim, Ki-Bong | - |
dc.contributor.author | Lee, Whal | - |
dc.date.accessioned | 2012-05-30T02:28:25Z | - |
dc.date.available | 2012-05-30T02:28:25Z | - |
dc.date.issued | 2010-06 | - |
dc.identifier.citation | EUROPEAN HEART JOURNAL; Vol.31 12; 1520-1528 | ko_KR |
dc.identifier.issn | 0195-668X | - |
dc.identifier.uri | https://hdl.handle.net/10371/76610 | - |
dc.description.abstract | There has been growing attention for the development of functional tricuspid regurgitation (TR) long after left-sided valve surgery. We attempted to determine the long-term haemodynamic effects of corrective surgery for severe functional TR in patients who had prior left-sided valve surgery using cardiac magnetic resonance imaging (CMR). Thirty-one patients with severe functional TR (TR fraction of 46.0 +/- 16.2% by CMR) were analysed. CMR was performed within 1 month before and at a median 27.0 months after surgery. Long after TR surgery, 28 of the 31 patients had no or mild residual TR, two had mild-to-moderate TR, and one showed moderate TR. Remarkable reductions in the right ventricular (RV) end-diastolic volume index (RV-EDVI) (177.4 +/- 59.1 mL/m(2) vs. 118.2 +/- 31.2 mL/m(2), P < 0.001) and end-systolic volume index (RV-ESVI) (88.5 +/- 30.1 mL/m(2) vs. 67.2 +/- 31.0 mL/m(2), P=0.002) were observed, whereas RV ejection fraction (RV-EF) showed no change (49.7 +/- 8.3% vs. 44.9 +/- 12.5%, P=0.09). Pre-operative RV-EDVI (R=-0.86, P < 0.001) and RV-ESVI (R=-0.55, P=0.001) were significantly associated with their respective changes after corrective surgery. Post-surgery, a normal RV-EF was achieved in 14 patients (42.5%). Pre-operative RV-EDVI of 164 mL/m(2) effectively discriminated patients with normal RV-EF from those without post-surgery, with a sensitivity of 77% and a specificity of 72% (P=0.01). A significant rise in the left ventricular (LV) EDVI and cardiac index (CI) was found after surgery (from 92.9 +/- 24.4 to 123.2 +/- 31.6 mL/m(2) for LV-EDVI, P < 0.001; from 3.8 +/- 1.3 to 4.2 +/- 0.8 L/min/m(2) for CI, P=0.03). Functional capacity as assessed by NYHA class showed a significant improvement from 2.7 +/- 0.6 before surgery to 2.0 +/- 0.6 long after surgery (P < 0.001). Successful TR surgery can remarkably reduce RV volumes and preserve RV systolic function. In addition, successful TR surgery led to a significant rise in LV preload and CI, which may significantly contribute to a significant amelioration in the functional capacity of the patients. It seems that RV volume measurement by CMR is helpful for determining optimal timing for TR surgery. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | OXFORD UNIV PRESS | ko_KR |
dc.subject | Tricuspid regurgitation | ko_KR |
dc.subject | Magnetic resonance imaging | ko_KR |
dc.subject | Right ventricle | ko_KR |
dc.subject | Surgery | ko_KR |
dc.title | Assessment of haemodynamic effects of surgical correction for severe functional tricuspid regurgitation: cardiac magnetic resonance imaging study | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 김형관 | - |
dc.contributor.AlternativeAuthor | 김용진 | - |
dc.contributor.AlternativeAuthor | 박은아 | - |
dc.contributor.AlternativeAuthor | 배지선 | - |
dc.contributor.AlternativeAuthor | 이활 | - |
dc.contributor.AlternativeAuthor | 김경환 | - |
dc.contributor.AlternativeAuthor | 김기봉 | - |
dc.contributor.AlternativeAuthor | 손대원 | - |
dc.contributor.AlternativeAuthor | 안혁 | - |
dc.contributor.AlternativeAuthor | 박재형 | - |
dc.contributor.AlternativeAuthor | 박영배 | - |
dc.identifier.doi | 10.1093/eurheartj/ehq063 | - |
dc.citation.journaltitle | EUROPEAN HEART JOURNAL | - |
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dc.description.tc | 3 | - |
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