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Follicular dendritic cell sarcoma with immature T-cell proliferation

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dc.contributor.authorKim, Wook Youn-
dc.contributor.authorKim, Haeryoung-
dc.contributor.authorJeon, Yoon Kyung-
dc.contributor.authorKim, Chul-Woo-
dc.date.accessioned2012-06-01T07:45:11Z-
dc.date.available2012-06-01T07:45:11Z-
dc.date.issued2010-01-
dc.identifier.citationHUMAN PATHOLOGY; Vol.41 1; 129-133ko_KR
dc.identifier.issn0046-8177-
dc.identifier.urihttps://hdl.handle.net/10371/76718-
dc.description.abstractFollicular dendritic cell sarcoma is characterized by proliferation of spindled to ovoid cells reminiscent of follicular dendritic cells. However, the association of follicular dendritic cell sarcoma with a dense infiltration of immature T cells has not hitherto been reported. We report an unusual case of follicular dendritic cell sarcoma of the mesentery with immature T-cell proliferation in a 68-year-old man. The infiltrating immature T cells demonstrated expression of CD3, CD1a, TdT, and coexpression of CD4 and CD8 by immunohistochemistry. In addition, the patient was subsequently diagnosed with myasthenia gravis and paraneoplastic pemphigus and died of distant metastasis within 2 years after initial diagnosis of follicular dendritic cell sarcoma. The aggressive clinical course of this case contrasts with the indolent course of follicular dendritic cell sarcomas, and thus, the prognostic implications of follicular dendritic cell sarcoma with immature T-cell proliferation require clarification. The complication of myasthenia gravis and paraneoplastic pemphigus may suggest that immature T-cell proliferation has an autoimmunity-related systemic influence. (c) 2010 Elsevier Inc. All rights reserved.ko_KR
dc.description.sponsorshipThis work was supported by grants from the Korean Science and
Engineering Foundation (KOSEF) through the Tumor Immunity Medical
Research Center at Seoul National University College of Medicine.
ko_KR
dc.language.isoenko_KR
dc.publisherW B SAUNDERS CO-ELSEVIER INCko_KR
dc.subjectFollicular dendritic cell sarcomako_KR
dc.subjectImmature T cellsko_KR
dc.subjectPemphigusko_KR
dc.subjectMyasthenia gravisko_KR
dc.titleFollicular dendritic cell sarcoma with immature T-cell proliferationko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor김욱윤-
dc.contributor.AlternativeAuthor김혜령-
dc.contributor.AlternativeAuthor전윤경-
dc.contributor.AlternativeAuthor김철우-
dc.identifier.doi10.1016/j.humpath.2009.05.014-
dc.citation.journaltitleHUMAN PATHOLOGY-
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College of Medicine/School of Medicine (의과대학/대학원)Pathology (병리학전공)Journal Papers (저널논문_병리학전공)
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