S-Space College of Medicine/School of Medicine (의과대학/대학원) Obstetrics & Gynecology (산부인과전공) Journal Papers (저널논문_산부인과학전공)
Primary yolk sac tumor of the omentum: a case report and review of the literature
- Kim, Sang-Wook; Park, Ju-Hee; Lim, Myung-Chul; Park, Jeong-Yeol; Park, Sang-Yoon; Yoo, Chong-Woo
- Issue Date
- SPRINGER HEIDELBERG
- ARCHIVES OF GYNECOLOGY AND OBSTETRICS; Vol.279 2; 189-192
- Extraovarian yolk sac tumors (YSTs) arising in the omentum represent an exceedingly rare malignancy. A 37-year-old Korean woman was admitted with a history of lower abdominal pain of 3 weeks duration. Pelvic computerized tomography (CT) scanning reported a bilateral ovarian malignancy with peritoneal seeding. Exploration findings revealed a greater omental mass and the result of frozen biopsy was adenocarcinoma or mesothelioma. She was treated with supracolic omentectomy, bilateral salpingo-oophorectomy, pelvic and paraaortic lymph node dissection, multiple peritoneal biopsies and appendectomy. Histological evaluation of the specimen after operation exhibited typical patterns of YST and stained for alpha-fetoprotein (AFP) and cytokeratin. Four courses of bleomycin, etoposide, and cisplatin (BEP) combination chemotherapy repeated every 3 weeks were added to therapy and she has remained free of disease for 1 year after completion of the therapy. To our knowledge this is the fourth case of primary omental YST. A review of the literature indicates that the diagnosis of YST requires proper evaluations of tumor makers and a skilled pathologist for analysis of frozen sections.
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