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Oxidized Low-Density Lipoprotein and Oxidative Stress in the Development of Glomerulosclerosis
DC Field | Value | Language |
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dc.contributor.author | Lee, Hyun Soon | - |
dc.contributor.author | Song, Chi Young | - |
dc.date.accessioned | 2012-06-04T08:05:13Z | - |
dc.date.available | 2012-06-04T08:05:13Z | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | AMERICAN JOURNAL OF NEPHROLOGY; Vol.29 1; 62-70 | ko_KR |
dc.identifier.issn | 0250-8095 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76802 | - |
dc.description.abstract | Glomerulosclerosis frequently complicates most renal diseases and is characterized by mesangial matrix accumulation. Oxidized low-density lipoprotein (Ox-LDL) could induce oxidative stress and profibrotic gene expression in mesangial cells. This article will review our current understanding of the pathogenetic mechanisms of lipid-mediated glomerulosclerosis, emphasizing the fibrogenic signaling cascades triggered by Ox-LDL. In addition, therapeutic strategies to prevent the development of Ox-LDL-mediated glomerulosclerosis will be discussed. Copyright (C) 2008 S. Karger AG, Basel | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | KARGER | ko_KR |
dc.subject | Angiotensin II | ko_KR |
dc.subject | TGF-beta signaling | ko_KR |
dc.subject | Reactive aldehydes | ko_KR |
dc.subject | NADPH oxidase | ko_KR |
dc.subject | Dyslipidemia | ko_KR |
dc.subject | Mesangial matrix | ko_KR |
dc.title | Oxidized Low-Density Lipoprotein and Oxidative Stress in the Development of Glomerulosclerosis | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 이현순 | - |
dc.contributor.AlternativeAuthor | 송지영 | - |
dc.identifier.doi | 10.1159/000151277 | - |
dc.citation.journaltitle | AMERICAN JOURNAL OF NEPHROLOGY | - |
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dc.description.tc | 10 | - |
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