Publications
Detailed Information
Analysis of the transforming growth factor β1 gene L509 C/T polymorphism in patients with advanced-stage endometriosis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jin Ju | - |
dc.contributor.author | Choi, Young Min | - |
dc.contributor.author | Choung, Seon Ha | - |
dc.contributor.author | Yoon, Sang Ho | - |
dc.contributor.author | Ku, Seung Yup | - |
dc.contributor.author | Moon, Shin Yong | - |
dc.contributor.author | Kim, Jung Gu | - |
dc.contributor.author | Lee, Kyu Sup | - |
dc.date.accessioned | 2012-06-05T00:23:34Z | - |
dc.date.available | 2012-06-05T00:23:34Z | - |
dc.date.issued | 2010-05-01 | - |
dc.identifier.citation | FERTILITY AND STERILITY; Vol.93 7; 2121-2124 | ko_KR |
dc.identifier.issn | 0015-0282 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76814 | - |
dc.description.abstract | Objective: To investigate whether the transforming growth factor beta (TGF-beta) gene -509 C/T polymorphism is associated with susceptibility to advanced-stage endometriosis. Design: Case-control study. Setting: University department of obstetrics and gynecology. Patient(s): Women with advanced-stage endometriosis (n = 485) and without endometriosis (n 352). Intervention(s): Genotyping by real-time polymerase chain reaction using a Taqman assay. Main Outcome Measure(s): Genotype distribution and allele frequency of the -509 C/T polymorphism in the TGF-beta 1 gene. Result(s): The genotype distribution of the TGF-beta 1 gene -509 C/T polymorphism in the endometriosis group was not different from that of the control group (CC/CT/TT rates were 29.3%/48.2%/22.5% and 27.3%/50.3%/22.4% for the endometriosis and control groups, respectively). Further subgroup analyses according to the stage of endometriosis or bilaterality of ovarian endometrioma also revealed no significant differences in the genotype distribution between each of the subgroups and the control group. Conclusion(s): These results suggest that the TGF-beta 1 -509 C/T polymorphism may not be associated with an increased risk for advanced-stage endometriosis. (Fertil Steril (R) 2010;93:2121-4. (C)2010 by American Society for Reproductive Medicine.) | ko_KR |
dc.description.sponsorship | Supported by a grant from the Korea Health 21 R&D Project, Ministry of
Health and Welfare, Republic of Korea (01-PJ10-PG6–01GN13–0002). | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | ELSEVIER SCIENCE INC | ko_KR |
dc.subject | Endometriosis | ko_KR |
dc.subject | transforming growth factor β1 | ko_KR |
dc.subject | polymorphism | ko_KR |
dc.title | Analysis of the transforming growth factor β1 gene L509 C/T polymorphism in patients with advanced-stage endometriosis | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 김진주 | - |
dc.contributor.AlternativeAuthor | 최영민 | - |
dc.contributor.AlternativeAuthor | 정선하 | - |
dc.contributor.AlternativeAuthor | 윤상호 | - |
dc.contributor.AlternativeAuthor | 이규섭 | - |
dc.contributor.AlternativeAuthor | 구승엽 | - |
dc.contributor.AlternativeAuthor | 김정구 | - |
dc.contributor.AlternativeAuthor | 문신용 | - |
dc.identifier.doi | 10.1016/j.fertnstert.2009.01.082 | - |
dc.citation.journaltitle | FERTILITY AND STERILITY | - |
dc.description.citedreference | Bertolino P, 2005, CHEST, V128, p585S | - |
dc.description.citedreference | Kim SH, 2005, HUM REPROD, V20, P2904, DOI 10.1093/humrep/dei146 | - |
dc.description.citedreference | Shin AS, 2005, CANCER EPIDEM BIOMAR, V14, P1567 | - |
dc.description.citedreference | Hsieh YY, 2005, BIOCHEM GENET, V43, P203, DOI 10.1007/s10528-005-5211-x | - |
dc.description.citedreference | Elliott RL, 2005, J CLIN ONCOL, V23, P2078, DOI 10.1200/JCO.2005.02.047 | - |
dc.description.citedreference | Salanti G, 2005, GENET MED, V7, P13 | - |
dc.description.citedreference | Nap AW, 2004, J CLIN ENDOCR METAB, V89, P1089, DOI 10.1210/jc.2003-031406 | - |
dc.description.citedreference | Bischoff F, 2004, ANN NY ACAD SCI, V1034, P284, DOI 10.1196/annals.1335.030 | - |
dc.description.citedreference | Goumans MJ, 2003, TRENDS CARDIOVAS MED, V13, P301 | - |
dc.description.citedreference | Shi YG, 2003, CELL, V113, P685 | - |
dc.description.citedreference | MISSMER SA, 2003, OBSTET GYN CLIN N AM, V30, P1 | - |
dc.description.citedreference | Hadfield RM, 2001, MOL HUM REPROD, V7, P1073 | - |
dc.description.citedreference | Zondervan KT, 2001, CURR OPIN OBSTET GYN, V13, P309 | - |
dc.description.citedreference | Campbell I, 2001, RAPID PROTOTYPING J, V7, P5 | - |
dc.description.citedreference | Grainger DJ, 1999, HUM MOL GENET, V8, P93 | - |
dc.description.citedreference | Taylor RN, 1997, ANN NY ACAD SCI, V828, P194 | - |
dc.description.citedreference | *AM SOC REPR MED, 1996, FERTIL STERIL, V1997, P817 | - |
dc.description.citedreference | MARSHBURN PB, 1994, AM J OBSTET GYNECOL, V170, P1152 | - |
dc.description.citedreference | HAMMOND MG, 1993, AM J OBSTET GYNECOL, V168, P1131 | - |
dc.description.citedreference | OOSTERLYNCK DJ, 1992, FERTIL STERIL, V58, P290 | - |
dc.description.citedreference | KANZAKI H, 1992, AM J OBSTET GYNECOL, V167, P257 | - |
dc.description.citedreference | TANAKA E, 1992, GYNECOL OBSTET INVES, V34, P27 | - |
dc.description.citedreference | ROOK AH, 1986, J IMMUNOL, V136, P3916 | - |
dc.description.citedreference | FUJII D, 1986, SOMAT CELL MOLEC GEN, V12, P281 | - |
dc.description.tc | 3 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.