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Patients with an asymptomatic short cervix (<= 15 mm) have a high rate of subclinical intraamniotic inflammation: implications for patient counseling
DC Field | Value | Language |
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dc.contributor.author | Vaisbuch, Edi | - |
dc.contributor.author | Hassan, Sonia S. | - |
dc.contributor.author | Mazaki-Tovi, Shali | - |
dc.contributor.author | Nhan-Chang, Chia-Ling | - |
dc.contributor.author | Chaiworapongsa, Tinnakorn | - |
dc.contributor.author | Yeo, Lami | - |
dc.contributor.author | Yoon, Bo Hyun | - |
dc.contributor.author | Romero, Roberto | - |
dc.contributor.author | Mittal, Pooja | - |
dc.contributor.author | Dong, Zhong | - |
dc.contributor.author | Kusanovic, Juan Pedro | - |
dc.date.accessioned | 2012-06-05T00:34:35Z | - |
dc.date.available | 2012-06-05T00:34:35Z | - |
dc.date.issued | 2010-05 | - |
dc.identifier.citation | AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY; Vol.202 5; - | ko_KR |
dc.identifier.issn | 0002-9378 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76816 | - |
dc.description.abstract | OBJECTIVE: The objective of the study was to determine the frequency and clinical significance of intraamniotic inflammation in asymptomatic women with a sonographic short cervix (SCX) in the midtrimester. STUDY DESIGN: This cohort study included 47 asymptomatic women (14-24 weeks) with an SCX (<= 15 mm) who underwent amniocentesis. Women with multiple gestation, cerclage, or cervical dilatation greater than 2 cm were excluded. Intraamniotic inflammation was defined as an elevated amniotic fluid (AF) matrix metalloproteinase-8 concentration (>23 ng/mL). RESULTS: (1) intraamniotic infection was found in 4.3% of patients; (2) among patients with a negative AF culture, the prevalence of intraamniotic inflammation was 22.2%; and (3) patients with a negative AF culture, but with intraamniotic inflammation, had a higher rate of delivery within 7 days (40% vs 5.7%; P = .016) and a shorter median diagnosis-to-delivery interval than those without intraamniotic inflammation (18 vs 42 days; P = .01). CONCLUSION: Twenty-two percent of patients with a midtrimester SCX have intraamniotic inflammation. The risk of preterm delivery within 7 days for these patients is 40%. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | MOSBY-ELSEVIER | ko_KR |
dc.subject | cervical length | ko_KR |
dc.subject | matrix metalloproteinase-8 | ko_KR |
dc.subject | MMP-8 | ko_KR |
dc.subject | intraamniotic inflammation | ko_KR |
dc.subject | pregnancy | ko_KR |
dc.subject | preterm delivery | ko_KR |
dc.subject | prematurity | ko_KR |
dc.title | Patients with an asymptomatic short cervix (<= 15 mm) have a high rate of subclinical intraamniotic inflammation: implications for patient counseling | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 윤보현 | - |
dc.identifier.doi | 10.1016/j.ajog.2010.02.007 | - |
dc.citation.journaltitle | AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | - |
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dc.description.tc | 0 | - |
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