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Thalamic changes in temporal lobe epilepsy with and without hippocampal sclerosis: A diffusion tensor imaging study
DC Field | Value | Language |
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dc.contributor.author | Kim, Chi Heon | - |
dc.contributor.author | Koo, Bang-Bon | - |
dc.contributor.author | Chung, Chun Kee | - |
dc.contributor.author | Lee, Jong-Min | - |
dc.contributor.author | Lee, Sang Kun | - |
dc.contributor.author | Kim, June Sic | - |
dc.date.accessioned | 2012-06-13T07:44:41Z | - |
dc.date.available | 2012-06-13T07:44:41Z | - |
dc.date.issued | 2010-06 | - |
dc.identifier.citation | EPILEPSY RESEARCH; Vol.90 01월 02일; 21-27 | ko_KR |
dc.identifier.issn | 0920-1211 | - |
dc.identifier.uri | https://hdl.handle.net/10371/77041 | - |
dc.description.abstract | Objective: The seizure network may be different between temporal lobe epilepsy with hippocampal sclerosis (TLE + HS) and without HS (TLE - HS). Chronic seizure activity may alter the diffusion properties of a seizure network. The thalamus is known to have an anatomical connection to the medial temporal area and to play a role in seizure modulation. This study aimed to evaluate differences in thalamic changes between TLE + HS and TLE - HS with diffusion tensor imaging (DTI). Methods: Nine patients with TLE + HS and nine patients with TLE - HS were included in the study. All patients underwent surgery with good seizure outcomes. Hippocampal sclerosis was verified pathologically. Sixteen right-handed, normal subjects were enrolled as controls. DTI was acquired using 3.0 T MRI. The mean diffusivity (MD) and fractional anisotropy (FA) were calculated in the center of the bilateral thalamus with the DTIstudio program. Results: The MD of bilateral thalami increased in both TLE groups compared to controls (p<0.05), while FA values did not differ from controls. The MD of the thalamus ipsilateral to the epileptogenic side was higher in the TLE + HS group than in the TLE - HS group (p=0.007). Onset age, seizure duration, seizure frequency and total seizure number were not correlated with FA and MD changes (p>0.05). Conclusion: Bilateral thalamic diffusion properties are altered in temporal lobe epilepsy. The presence of hippocampal sclerosis enhances the change ipsilaterally. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | ELSEVIER SCIENCE BV | ko_KR |
dc.subject | Magnetic resonance imaging | ko_KR |
dc.subject | Temporal lobe epilepsy | ko_KR |
dc.subject | Thalamus | ko_KR |
dc.subject | Tensor | ko_KR |
dc.subject | Hippocampus | ko_KR |
dc.title | Thalamic changes in temporal lobe epilepsy with and without hippocampal sclerosis: A diffusion tensor imaging study | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 김치헌 | - |
dc.contributor.AlternativeAuthor | 구방본 | - |
dc.contributor.AlternativeAuthor | 정천기 | - |
dc.contributor.AlternativeAuthor | 이종민 | - |
dc.contributor.AlternativeAuthor | 김준식 | - |
dc.contributor.AlternativeAuthor | 이상건 | - |
dc.identifier.doi | 10.1016/j.eplepsyres.2010.03.002 | - |
dc.citation.journaltitle | EPILEPSY RESEARCH | - |
dc.description.citedreference | Bertram EH, 2009, EPILEPSY BEHAV, V14, P32, DOI 10.1016/j.yebeh.2008.09.017 | - |
dc.description.citedreference | Nilsson D, 2008, EPILEPSY RES, V81, P128, DOI 10.1016/j.eplepsyres.2008.05.002 | - |
dc.description.citedreference | Labate A, 2008, NEUROLOGY, V71, P1094 | - |
dc.description.citedreference | Riederer F, 2008, NEUROLOGY, V71, P419 | - |
dc.description.citedreference | Gong G, 2008, EPILEPSY RES, V80, P184, DOI 10.1016/j.eplepsyres.2008.04.002 | - |
dc.description.citedreference | Keller SS, 2008, EPILEPSIA, V49, P741, DOI 10.1111/j.1528-1167.2007.01485.x | - |
dc.description.citedreference | Focke NK, 2008, NEUROIMAGE, V40, P728, DOI 10.1016/j.neuroimage.2007.12.031 | - |
dc.description.citedreference | Oouchi H, 2007, AM J NEURORADIOL, V28, P1102, DOI 10.3174/ajnr.A0488 | - |
dc.description.citedreference | Kim CH, 2007, J NEUROSURG, V106, P111 | - |
dc.description.citedreference | Gross DW, 2006, EPILEPSIA, V47, P1360, DOI 10.1111/j.1528-1167.2006.00603.x | - |
dc.description.citedreference | Mueller SG, 2006, EPILEPSIA, V47, P900 | - |
dc.description.citedreference | Kimiwada T, 2006, EPILEPSIA, V47, P167 | - |
dc.description.citedreference | Thivard L, 2005, NEUROIMAGE, V28, P682, DOI 10.1016/j.neuroimage.2005.06.045 | - |
dc.description.citedreference | Concha L, 2005, ANN NEUROL, V57, P188, DOI 10.1002/ana.20334 | - |
dc.description.citedreference | PALMINI A, 2004, NEUROLOGY, V62, P2 | - |
dc.description.citedreference | Kim YK, 2003, J NUCL MED, V44, P1006 | - |
dc.description.citedreference | Natsume J, 2003, NEUROLOGY, V60, P1296 | - |
dc.description.citedreference | Choi JY, 2003, EUR J NUCL MED MOL I, V30, P581, DOI 10.1007/s00259-002-1079-8 | - |
dc.description.citedreference | Arfanakis K, 2002, MAGN RESON IMAGING, V20, P511 | - |
dc.description.citedreference | Yoo SY, 2002, AM J NEURORADIOL, V23, P809 | - |
dc.description.citedreference | Bertram EH, 2001, EPILEPSIA, V42, P967 | - |
dc.description.citedreference | Kim YH, 2001, KOREAN J RADIOL, V2, P63 | - |
dc.description.citedreference | Rugg-Gunn FJ, 2001, BRAIN, V124, P627 | - |
dc.description.citedreference | Eriksson SH, 2001, BRAIN, V124, P617 | - |
dc.description.citedreference | Diehl B, 2001, EPILEPSIA, V42, P21 | - |
dc.description.citedreference | Newberg AB, 2000, J NUCL MED, V41, P1964 | - |
dc.description.citedreference | Men S, 2000, AM J NEURORADIOL, V21, P1837 | - |
dc.description.citedreference | Diehl B, 1999, EPILEPSIA, V40, P1667 | - |
dc.description.citedreference | Bertram EH, 1999, NEUROSCIENCE, V92, P15 | - |
dc.description.citedreference | Baulac M, 1998, ANN NEUROL, V44, P223 | - |
dc.description.citedreference | Ho SS, 1998, NEUROLOGY, V50, P748 | - |
dc.description.citedreference | ENGEL J, 1993, SURG TREATMENT EPILE, P553 | - |
dc.description.citedreference | OLDFIELD RC, 1971, NEUROPSYCHOLOGIA, V9, P97 | - |
dc.description.tc | 3 | - |
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