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Little Response of Cerebral Metastasis from Hepatocellular Carcinoma to Any Treatments
DC Field | Value | Language |
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dc.contributor.author | Han, Jung Ho | - |
dc.contributor.author | Kim, Dong Gyu | - |
dc.contributor.author | Park, Jung Cheol | - |
dc.contributor.author | Chung, Hyun-Tai | - |
dc.contributor.author | Chung, Young Seob | - |
dc.contributor.author | Paek, Sun Ha | - |
dc.date.accessioned | 2012-06-13T08:09:02Z | - |
dc.date.available | 2012-06-13T08:09:02Z | - |
dc.date.issued | 2010-05 | - |
dc.identifier.citation | JOURNAL OF KOREAN NEUROSURGICAL SOCIETY; Vol.47 5; 325-331 | ko_KR |
dc.identifier.issn | 2005-3711 | - |
dc.identifier.uri | https://hdl.handle.net/10371/77045 | - |
dc.description.abstract | Objective : We retrospectively evaluated the survival outcome of patients with brain metastasis from hepatocellular carcinoma (HCC). Methods : Between 1991 and 2007, a total of 20 patients were diagnosed as having brain metastasis from HCC. The mean age of the patients was 55 +/- 13 years, and 17(85.0%) were men. Seventeen (85.0%) patients had already extracranial metastases. The median time from diagnosis of HCC to brain metastasis was 18.5 months. Fourteen (70.0%) patients had stroke-like presentation due to intracerebral hemorrhage (ICH). Ten (50.0%) patients had single or solitary brain metastasis. Among a total of 34 brain lesions, 31 (91.2%) lesions had the hemorrhagic components. Results : The median survival time was 8 weeks (95% Cl, 5.08-10.92), and the actuarial survival rates were 85.0%, 45.0%, 22.5%, and 8.4% at 4, 12, 24, and 54 weeks. Age < 60 years, treatment of the primary and/or extracranial lesions, and recurrent ICH were the possible prognostic factors (p = 0.044, p < 0.001, and p = 0.111, respectively). The median progression-free survival (PFS) time was 3 months (95% Cl, 0.95-5.05). Conclusion : The overall survival of the patients with brain metastasis from HCC was very poor with median survival time being only 8 weeks. However, the younger patients less than 60 years and/or no extracranial metastases seem to be a positive prognostic factor. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | KOREAN NEUROSURGICAL SOC | ko_KR |
dc.subject | Brain metastasis | ko_KR |
dc.subject | Prognostic factor | ko_KR |
dc.subject | Hepatocellular carcinoma | ko_KR |
dc.subject | Survival outcome | ko_KR |
dc.title | Little Response of Cerebral Metastasis from Hepatocellular Carcinoma to Any Treatments | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 한정호 | - |
dc.contributor.AlternativeAuthor | 김동규 | - |
dc.contributor.AlternativeAuthor | 박정철 | - |
dc.contributor.AlternativeAuthor | 정현태 | - |
dc.contributor.AlternativeAuthor | 백선하 | - |
dc.contributor.AlternativeAuthor | 정영섭 | - |
dc.identifier.doi | 10.3340/jkns.2010.47.5.325 | - |
dc.citation.journaltitle | JOURNAL OF KOREAN NEUROSURGICAL SOCIETY | - |
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dc.description.tc | 2 | - |
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