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Ischemic stroke patterns and hemodynamic features in patients with small vertebrobasilar artery

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dc.contributor.authorPark, Jong-Ho-
dc.contributor.authorRoh, Jae-Kyu-
dc.contributor.authorKwon, Hyung-Min-
dc.date.accessioned2012-06-18T06:06:39Z-
dc.date.available2012-06-18T06:06:39Z-
dc.date.issued2009-12-15-
dc.identifier.citationJOURNAL OF THE NEUROLOGICAL SCIENCES; Vol.287; 227-235ko_KR
dc.identifier.issn0022-510X-
dc.identifier.urihttps://hdl.handle.net/10371/77127-
dc.description.abstractBackground: To determine the role of small vertebrobasilar artery (SVBA) in patients with posterior circulation stroke (PCS), we evaluated the ischemic patterns, collateral features, and stroke mechanisms in PCS patients with SVBA. Methods: Ischemic findings on magnetic resonance (MR) imaging were correlated with 3D time-of-flight/contrast-enhanced MR angiography and/or catheter angiography in 18 patients (mean age, 68.0 +/- 11.8 years; 9 males). SVBA (lumen diameter of <3 mm) was compared with stenotic normal-sized VBA (NVBA) in 14 PCS patients. Results: Ischemic lesions were predominantly observed in the cerebellum and/or medulla (vertebral artery (VA) territory). All subjects had fetal posterior circulation (FPC) from the internal carotid artery to the posterior cerebral artery. Sixteen patients (88.9%) had distal or diffuse VA stenosis/occlusion. In 14 patients (77.8%), long circumferential artery (LCA) was prominently observed. In atherothrombotic patients, infratentorial PCS might occur following artery-to-artery embolism from the low-flowed or stenotic VA to LCA. Ischemic patterns between subjects with and without VA disease were almost similar. As the degree of VA disease increased, the frequency of LCA prominence showed an increased tendency (P = 0.003). Relatively small, scattered infarcts were observed in patients with SVBA than in those with stenotic NVBA. Conclusions: FPC does not protect against infratentorial PCS. Regardless of extensive arterial lesions, relatively small infarcts may be due to previously established collaterals from the LCA, which could compensate for the defects in the infratentorial area.ko_KR
dc.language.isoenko_KR
dc.publisherELSEVIER SCIENCE BVko_KR
dc.subjectSmall vertebrobasilar arteryko_KR
dc.subjectLong circumferential arteryko_KR
dc.subjectAngiographyko_KR
dc.subjectMR imagingko_KR
dc.subjectIschemic patternko_KR
dc.titleIschemic stroke patterns and hemodynamic features in patients with small vertebrobasilar arteryko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor박종호-
dc.contributor.AlternativeAuthor노재규-
dc.contributor.AlternativeAuthor권형민-
dc.identifier.doi10.1016/j.jns.2009.07.007-
dc.citation.journaltitleJOURNAL OF THE NEUROLOGICAL SCIENCES-
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Neurology (신경과학교실)Journal Papers (저널논문_신경과학교실)
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