Browse

White matter lesions and poor outcome after intracerebral hemorrhage A nationwide cohort study

DC Field Value Language
dc.contributor.authorLee, S. -H.-
dc.contributor.authorKim, B. J.-
dc.contributor.authorRyu, W. -S.-
dc.contributor.authorKim, C. K.-
dc.contributor.authorPark, B. -J.-
dc.contributor.authorYoon, B. -W.-
dc.contributor.authorKim, N.-
dc.date.accessioned2012-06-26T05:03:05Z-
dc.date.available2012-06-26T05:03:05Z-
dc.date.issued2010-05-11-
dc.identifier.citationNEUROLOGY; Vol.74 19; 1502-1510ko_KR
dc.identifier.issn0028-3878-
dc.identifier.urihttps://hdl.handle.net/10371/77426-
dc.description.abstractBackground: The ability to predict poor outcome is important for patient care and treatment decision-making in cases of intracerebral hemorrhage (ICH). Previous studies have included relatively brief follow-up periods and small numbers of patients, and are limited in terms of considerations regarding individual brain vulnerabilities. Methods: The authors prospectively enrolled 1,321 ICH patients nationwide from 33 hospitals. Clinical, laboratory, and imaging variables, including white matter lesions (WMLs), were collected at admission. Immediate outcome after ICH was measured using total Glasgow Coma Scale (GCS) score at admission, early outcome using 30-day mortality, and long-term outcome using relative risk for mortality. The vital status of included patients was ascertained on December 31, 2006, using Korean National Death Certificates (mean follow-up, 32.6 months). Results: Of the 1,321 ICH patients included, 352 (27.8%) presented with a moderate GCS score (8.5-12.4) and 249 (19.7%) with a severe GCS score (<= 8.4). The mortality rate was 9.1% at day 30 post-ICH and 381 patients (29.8%) had died up to the end of December 2006. Extensive WMLs were associated with severe GCS scores at admission (odds ratio [OR] 2.45, 95% confidence interval [Cl] 1.73-3.46), 30-day mortality (OR 2.52, 95% Cl 1.33-4.75), and the relative risk for mortality (RR 2.61, 95% Cl 1.79-3.82) after adjusting for relevant covariates. Conclusions: These findings suggest that white matter lesions, which may reflect the vulnerability of individual brains to pathologic insults, should be considered when assessing immediate, early, and long-term outcomes after intracerebral hemorrhage.ko_KR
dc.language.isoenko_KR
dc.publisherLIPPINCOTT WILLIAMS & WILKINSko_KR
dc.titleWhite matter lesions and poor outcome after intracerebral hemorrhage A nationwide cohort studyko_KR
dc.typeArticleko_KR
dc.identifier.doi10.1212/WNL.0b013e3181dd425a-
dc.citation.journaltitleNEUROLOGY-
dc.description.citedreferenceLee SH, 2010, DIABETOLOGIA, V53, P429, DOI 10.1007/s00125-009-1617-z-
dc.description.citedreferenceRost NS, 2008, STROKE, V39, P2304, DOI 10.1161/STROKEAHA.107.512202-
dc.description.citedreferenceBarton CW, 2007, ACAD EMERG MED, V14, P695, DOI 10.1197/j.aem.2007.03.1358-
dc.description.citedreferenceZahuranec DB, 2007, NEUROLOGY, V68, P1651-
dc.description.citedreferenceRuiz-Sandoval JL, 2007, STROKE, V38, P1641, DOI 10.1161/STROKEAHA.106.478222-
dc.description.citedreferencePalumbo V, 2007, NEUROLOGY, V68, P1020-
dc.description.citedreferenceYoon BW, 2007, NEUROLOGY, V68, P146, DOI 10.1212/01.wnl.0000250351.38999.f2-
dc.description.citedreferenceFlaherty ML, 2006, NEUROLOGY, V66, P1182-
dc.description.citedreferenceOvbiagele B, 2006, CEREBROVASC DIS, V22, P83, DOI 10.1159/000093235-
dc.description.citedreferenceKALARIA RN, 2006, J CLIN NEUROL, V2, P1-
dc.description.citedreferenceAriesen MJ, 2005, J NEUROL NEUROSUR PS, V76, P839, DOI 10.1136/jnnp.2004.048223-
dc.description.citedreferenceRoquer J, 2005, J NEUROL, V252, P412, DOI 10.1007/s00415-005-0659-5-
dc.description.citedreferenceGALLEGO J, 2005, CEREBROVASC DIS, V20, P1-
dc.description.citedreferenceSmith EE, 2004, NEUROLOGY, V63, P1606-
dc.description.citedreferenceKidwell CS, 2004, JAMA-J AM MED ASSOC, V292, P1823-
dc.description.citedreferenceGreenland P, 2004, JAMA-J AM MED ASSOC, V291, P210-
dc.description.citedreferenceKASE CS, 2004, STROKE PATHOPHYSIOLO, P327-
dc.description.citedreferenceInagawa T, 2003, NEUROSURGERY, V53, P1283, DOI 10.1227/01.NEU.0000093825.04365.F3-
dc.description.citedreferenceCheung RTF, 2003, STROKE, V34, P1717, DOI 10.1161/01.STR.0000078657.22835.B9-
dc.description.citedreferenceWardlaw JM, 2003, STROKE, V34, P806, DOI 10.1161/01.STR.0000058480.77236.B3-
dc.description.citedreferenceINAGAWA T, 2003, NEUROSURGERY, V53, P1297-
dc.description.citedreferenceHemphill JC, 2001, STROKE, V32, P891-
dc.description.citedreferenceBriley DP, 2000, NEUROLOGY, V54, P90-
dc.description.citedreferenceGorter JW, 1999, NEUROLOGY, V53, P1319-
dc.description.citedreferenceBroderick JP, 1999, STROKE, V30, P905-
dc.description.citedreferenceLeys D, 1999, EUR NEUROL, V42, P67-
dc.description.citedreferencevan Gijn J, 1998, NEUROLOGY, V51, pS3-
dc.description.citedreferenceMeredith W, 1998, J TRAUMA, V44, P839-
dc.description.citedreferenceMEREDITH W, 1998, J TRAUMA, V44, P844-
dc.description.citedreferenceQureshi AI, 1997, STROKE, V28, P961-
dc.description.citedreferenceTATEMICHI TK, 1994, NEUROLOGY, V44, P1885-
dc.description.citedreferenceVANSWIETEN JC, 1992, ANN NEUROL, V32, P177-
dc.description.citedreferenceCAPLAN LR, 1992, LANCET, V339, P656-
dc.description.citedreferenceVANSWIETEN JC, 1990, J NEUROL NEUROSUR PS, V53, P1080-
dc.description.citedreferenceSCHUTZ H, 1990, STROKE, V21, P1412-
dc.description.citedreferencePETERSON B, 1990, APPL STAT-J ROY ST C, V39, P205-
dc.description.citedreferenceSELEKLER K, 1989, STROKE, V20, P1016-
dc.description.citedreferenceFAZEKAS F, 1987, AM J ROENTGENOL, V149, P351-
dc.description.citedreferenceHACHINSKI VC, 1987, ARCH NEUROL-CHICAGO, V44, P21-
dc.description.citedreferenceBROTT T, 1986, STROKE, V17, P1078-
dc.description.citedreferenceMOHR JP, 1978, NEUROLOGY, V28, P754-
dc.description.tc8-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Preventive Medicine (예방의학전공)Journal Papers (저널논문_예방의학전공)
Files in This Item:
There are no files associated with this item.
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse