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Clinical outcomes after Ahmed valve implantation in refractory paediatric glaucoma

Cited 13 time in Web of Science Cited 18 time in Scopus
Authors
Yang, H. K.; Park, K. H.
Issue Date
2009-06
Publisher
NATURE PUBLISHING GROUP
Citation
EYE; Vol.23 6; 1427-1435
Keywords
Ahmed valve implantationintraocular pressurepaediatric glaucomaglaucoma drainage device
Abstract
Purpose To evaluate clinical outcomes after Ahmed valve implantation in refractory paediatric glaucoma. Methods A retrospective review was conducted on 34 eyes from 29 patients with refractory glaucoma, who were younger than 18 years of age and who underwent Ahmed valve implantation. The main outcome measures were intraocular pressures (IOPs) and the number of glaucoma medications used. Qualified success was defined as IOP <= 21 mm Hg regardless of the number of glaucoma medications. Complete success was defined as IOP <= 21 mm Hg without glaucoma medication. Results Mean age at operation was 5.5 years (range, 0-16). Fifteen eyes (44.1%) had undergone previous glaucoma surgery before Ahmed valve implantation. Mean follow-up time was 29.1 months (range, 3-31). IOP was reduced from a preoperative mean of 37.5 +/- 7.3 to 18.4 +/- 7.3 mm Hg at 6 months postoperatively (P < 0.01). At 12 months after surgery, the success rates were 63.3% (qualified success) and 13.3% (complete success). The cumulative probabilities of qualified success at 6, 12, and 24 months after Ahmed valve implantation were 89.0, 68.6, and 45.7%, respectively. The median time of survival was 19.6 +/- 0.9 months. Conclusions Ahmed valve implantation is effective in lowering IOP in refractory paediatric glaucoma, with limited survival after long-term follow-up. Addition of a second Ahmed valve may be effective in the management of failure after primary implantation. Eye (2009) 23, 1427-1435; doi:10.1038/eye.2008.261; published online 29 August 2008
ISSN
0950-222X
Language
English
URI
https://hdl.handle.net/10371/77990
DOI
https://doi.org/10.1038/eye.2008.261
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College of Medicine/School of Medicine (의과대학/대학원)Ophthalmology (안과학전공)Journal Papers (저널논문_안과학전공)
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