Publications

Detailed Information

Antibacterial Activity and Mechanism of Action of the Silver Ion in Staphylococcus aureus and Escherichia coli

DC Field Value Language
dc.contributor.authorJung, Woo Kyung-
dc.contributor.authorKoo, Hye Cheong-
dc.contributor.authorKim, Ki Woo-
dc.contributor.authorShin, Sook-
dc.contributor.authorKim, So Hyun-
dc.contributor.authorPark, Yong Ho-
dc.date.accessioned2009-08-25T07:54:08Z-
dc.date.available2009-08-25T07:54:08Z-
dc.date.issued2008-
dc.identifier.citationAppl. Environ. Microbiol. 74:2171-2178en
dc.identifier.issn0099-2240-
dc.identifier.urihttps://hdl.handle.net/10371/7803-
dc.description.abstractThe antibacterial effect and mechanism of action of a silver ion solution that was electrically generated were investigated for Staphylococcus aureus and Escherichia coli by analyzing the growth, morphology, and ultrastructure of the bacterial cells following treatment with the silver ion solution. Bacteria were exposed to the silver ion solution for various lengths of time, and the antibacterial effect of the solution was tested using the conventional plate count method and flow cytometric (FC) analysis. Reductions of more than 5 log10 CFU/ml of both S. aureus and E. coli bacteria were confirmed after 90 min of treatment with the silver ion solution. Significant reduction of S. aureus and E. coli cells was also observed by FC analysis; however, the reduction rate determined by FC analysis was less than that determined by the conventional plate count method. These differences may be attributed to the presence of bacteria in an active but nonculturable (ABNC) state after treatment with the silver ion solution. Transmission electron microscopy showed considerable changes in the bacterial cell membranes upon silver ion treatment, which might be the cause or consequence of cell death. In conclusion, the results of the present study suggest that silver ions may cause S. aureus and E. coli bacteria to reach an ABNC state and eventually die.en
dc.description.sponsorshipWe thank Young Hwan Paik for his technical assistance.
This study was supported by Korea Research Foundation grants
(KRF-2006-005-J02903 and KRF-2007-331-E00254), a grant from the
Technology Development Program for Agriculture and Forestry provided
by the Ministry of Agriculture and Forestry (grant no. 305003–3),
and the Korea Bio-Hub Program of the Korea Ministry of Commerce,
Industry Energy (2005-B0000002). Additional support was provided by
the Research Institute of Veterinary Science, Department of Veterinary
Microbiology, College of Veterinary Medicine, and the BK21
Program for Veterinary Science, Seoul National University.
en
dc.language.isoen-
dc.publisherAmerican Society for Microbiologyen
dc.titleAntibacterial Activity and Mechanism of Action of the Silver Ion in Staphylococcus aureus and Escherichia colien
dc.typeArticleen
dc.contributor.AlternativeAuthor정우경-
dc.contributor.AlternativeAuthor구혜정-
dc.contributor.AlternativeAuthor김기우-
dc.contributor.AlternativeAuthor신숙-
dc.contributor.AlternativeAuthor김소현-
dc.contributor.AlternativeAuthor박용호-
dc.identifier.doi10.1128/AEM.02001-07-
Appears in Collections:
Files in This Item:
There are no files associated with this item.

Altmetrics

Item View & Download Count

  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Share