Bizarre-looking violaceous nodular plaque on the hands: Unusual presentation of peripheral T-cell lymphoma, not otherwise specified

Abstract

Peripheral T-cell lymphoma (PTCL) refers to a heterogenous group of lymphoma originated from mature T cells. PTCL includes a series of rare but specified disorders, such as the enteropathy-associated T-cell lymphoma, the hepatosplenic T-cell lymphoma, the subcutaneous panniculitis-like T-cell lymphoma, the primary cutaneous peripheral T-cell lymphoma, rare subtypes and the extranodal natural killer (NK)⁄ T-cell lymphoma, nasal type. The term PTCL, not otherwise specified (PTCL-NOS) is now used in the revised World Health Organization classification instead of the previous name PTCL-unspecified and refers to unclassifiable PTCL that do not fit any of the defined entities.1–3 The most common presentation of PTCL-NOS is generalized lymph node enlargement, but extranodal involvement including bone marrow, liver, spleen and skin is also found.4 We report a case of PTCL-NOS with unusual cutaneous manifestation.