Publications
Detailed Information
Erythrocyte Malondialdehyde and Glutathione Levels in Vitiligo Patients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Jung Won | - |
dc.contributor.author | Nam, Kyung Mi | - |
dc.contributor.author | Choi, Hye Ryung | - |
dc.contributor.author | Huh, Sun Young | - |
dc.contributor.author | Youn, Sang Woong | - |
dc.contributor.author | Park, Kyoung Chan | - |
dc.contributor.author | Huh, Chang Hun | - |
dc.contributor.author | Kim, Shin Woo | - |
dc.date.accessioned | 2012-07-04T00:14:41Z | - |
dc.date.available | 2012-07-04T00:14:41Z | - |
dc.date.issued | 2010-08 | - |
dc.identifier.citation | ANNALS OF DERMATOLOGY; Vol.22, no.3; 279-283 | ko_KR |
dc.identifier.issn | 1013-9087 | - |
dc.identifier.uri | https://hdl.handle.net/10371/78331 | - |
dc.description.abstract | Background: Vitiligo is an acquired and progressive hypomelanotic disease that manifests as circumscribed depigmented patches on the skin. Although the precise mechanism remains to be elucidated, an imbalance of the oxidant/antioxidant system has been proposed as an important etiologic mechanism. Objective: The objective of this study was to evaluate the oxidant/antioxidant status of vitiligo patients at the erythrocyte level. Methods: Fifty-three vitiligo patients and 65 phototype-, age-, and sex- matched healthy controls were included in this study. Blood samples were collected from all subjects, and all patients were instructed to answer a questionnaire. Results: Erythrocyte levels of malondialdehyde (MDA) and glutathione (GSH) were measured. All patients were told to answer a questionnaire regarding their habitual behavior, including frequency of smoking and type of diet. We observed significantly lower levels of GSH in vitiligo patients, but the levels of MDA did not differ between patients and controls. Vitiligo patients who smoked showed significantly lower GSH levels compared to non-smoking patients, but the levels of MDA were unchanged between the 2 groups. Conclusion: From our results, we conclude that reduced erythrocytic or systemic GSH levels constitute a distinctive feature in vitiligo patients regardless of disease activity. | ko_KR |
dc.description.sponsorship | This study was supported by a grant (A084379) from the Korea
Health 21 R&D Project, Ministry of Health and Welfare, Republic of Korea. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | KOREAN DERMATOLOGICAL ASSOC | ko_KR |
dc.subject | Erythrocyte | ko_KR |
dc.subject | Glutathione | ko_KR |
dc.subject | Malondialdehyde | ko_KR |
dc.subject | Vitiligo | ko_KR |
dc.subject | Smoking | ko_KR |
dc.title | Erythrocyte Malondialdehyde and Glutathione Levels in Vitiligo Patients | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 신정원 | - |
dc.contributor.AlternativeAuthor | 남경미 | - |
dc.contributor.AlternativeAuthor | 최혜령 | - |
dc.contributor.AlternativeAuthor | 허선영 | - |
dc.contributor.AlternativeAuthor | 김신우 | - |
dc.contributor.AlternativeAuthor | 윤상웅 | - |
dc.contributor.AlternativeAuthor | 허창훈 | - |
dc.contributor.AlternativeAuthor | 박경찬 | - |
dc.identifier.doi | 10.5021/ad.2010.22.3.279 | - |
dc.citation.journaltitle | ANNALS OF DERMATOLOGY | - |
dc.description.citedreference | Dammak I, 2009, INT J DERMATOL, V48, P476 | - |
dc.description.citedreference | Sampogna F, 2008, BRIT J DERMATOL, V159, P351, DOI 10.1111/j.1365-2133.2008.08678.x | - |
dc.description.citedreference | Namazi MR, 2007, PIGM CELL RES, V20, P360, DOI 10.1111/j.1600-0749.2007.00408.x | - |
dc.description.citedreference | Park ES, 2007, J DERMATOL SCI, V47, P141, DOI 10.1016/j.jdermsci.2007.03.009 | - |
dc.description.citedreference | CASIANO CA, 2006, AUTOANTIBODIES AUTOI, P103 | - |
dc.description.citedreference | Solak ZA, 2005, CLIN EXP MED, V5, P99, DOI 10.1007/s10238-005-0072-5 | - |
dc.description.citedreference | Ongenae K, 2005, BRIT J DERMATOL, V152, P1165, DOI 10.1111/j.1365-2133.2005.06456.x | - |
dc.description.citedreference | Deakin SP, 2004, CLIN SCI, V107, P435 | - |
dc.description.citedreference | Yildirim M, 2004, J EUR ACAD DERMATOL, V18, P683, DOI 10.1111/j.1468-3083.2004.01080.x | - |
dc.description.citedreference | Cucchi ML, 2003, PIGM CELL RES, V16, P111 | - |
dc.description.citedreference | Yildirim M, 2003, J DERMATOL, V30, P104 | - |
dc.description.citedreference | Kose K, 2002, TOHOKU J EXP MED, V197, P9 | - |
dc.description.citedreference | HUANG CL, 2002, AM J CLIN DERMATOL, V3, P301 | - |
dc.description.citedreference | Simon HU, 2000, APOPTOSIS, V5, P415 | - |
dc.description.citedreference | Cucchi ML, 2000, PIGM CELL RES, V13, P28 | - |
dc.description.citedreference | Passi S, 1998, PIGM CELL RES, V11, P81 | - |
dc.description.citedreference | PICARDO M, 1994, PIGM CELL RES, V7, P110 | - |
dc.description.citedreference | MORRONE A, 1992, PIGM CELL RES, V5, P65 | - |
dc.description.citedreference | SCHALLREUTER KU, 1991, J INVEST DERMATOL, V97, P1081 | - |
dc.description.citedreference | CROSS CE, 1987, ANN INTERN MED, V107, P526 | - |
dc.description.tc | 0 | - |
- Appears in Collections:
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.